7-TM Receptors
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PF 514273
PF 514273 is a potent and selective CB1 receptor antagonist that inhibits food intake in vivo following oral administration. Learn MoreStarting at: $139.00
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SKF 83959 hydrobromide
SKF 83959 hydrobromide is a dopamine D1-like receptor partial agonist that act as an antagonist in vivo, producing anti-Parkinsonian effects and antagonizing the behavioral effects of cocaine. Learn MoreStarting at: $139.00
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Terfenadine
Terfenadine is a histamine H1 receptor antagonist, which also blocks KV11.1 (hERG) and Kir6 (KATP) channels (IC50 values are 204 nM and 1.2 μM respectively). Learn MoreStarting at: $49.00
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DEA
DEA is a potent endocannabinoid and anandamide analog that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (Ki = 34.4 nM). Learn MoreStarting at: $80.00
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SB 205607 dihydrobromide
SB 205607 dihydrobromide is the first described non-peptide δ1 opioid receptor agonist with very high affinity and selectivity for the δ1 subtype (Ki values are 1.12, 2320 and 1790 nM at δ1, μ and κ receptors respectively). Learn MoreStarting at: $175.00
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Tocrifluor T1117
Tocrifluor T1117 is a novel fluorescent form of AM 251, which conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543nm excitation (590nm emission), and displays GPR55 binding activity. Learn MoreStarting at: $200.00
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Telenzepine dihydrochloride
Telenzepine dihydrochloride is a selective high affinity muscarinic M1 receptor antagonist (Ki = 0.94 nM) which inhibits gastric acid secretion. Learn MoreStarting at: $50.00
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Doxepin hydrochloride
BMS 453 is a synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Learn MoreStarting at: $55.00
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N-Benzylnaltrindole hydrochloride
N-Benzylnaltrindole hydrochloride is a potent δ2-selective opioid receptor antagonist with a long duration of action in vivo. Learn MoreStarting at: $95.00
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A 77636 hydrochloride
A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively), which displays anti-Parkinsonian activity following oral administration in vivo. Learn MoreStarting at: $140.00
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MPPG
MTPG is a group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies. Learn MoreStarting at: $135.00
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SKF 83822 hydrobromide
SKF 83822 hydrobromide is a high affinity, selective dopamine D1-like receptor agonist. Learn MoreStarting at: $139.00
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Leelamine hydrochloride
Leelamine hydrochloride is a CB1 agonist which displaces binding of [3H]-SR141716A with an IC50 value of 2.86 μM. Learn MoreStarting at: $90.00
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(R)-(+)-Propranolol hydrochloride
(R)-(+)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol. Learn MoreStarting at: $69.00
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NIDA 41020
NIDA 41020 is a high affinity CB1 receptor antagonist (Ki = 4.1 nM), which exhibits significantly reduced lipophilicity compared to other CB1 antagonists. Learn MoreStarting at: $139.00
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Propranolol glycol
Propranolol glycol is a metabolite of propranolol. Learn MoreStarting at: $99.00
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2-Chloro-N6-cyclopentyladenosine
2-Chloro-N6-cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist (Ki values are 0.8, 2300 and 42 nM for human A1, A2A and A3 receptors respectively; EC50 = 18800 nM for hA2B). Learn MoreStarting at: $99.00
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VU 0357017 hydrochloride
VU 0357017 hydrochloride is a positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM), which displays no activity at M2-M5 at concentrations up to 30 μM. Learn MoreStarting at: $110.00
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VU 0255035
VU 0255035 is a highly selective muscarinic M1 antagonist (Ki = 14.87 nM), which targets the M1 orthosteric site and reduces pilocarpine-induced seizures in mice. Learn MoreStarting at: $110.00
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SDZ 21009
SDZ 21009 is a β-adrenoceptor and 5-HT1A/1B receptor antagonist. pKB/pA2 values are 8.3 and 8.0 for 5-HT1A and 5-HT1B receptors respectively. Learn MoreStarting at: $135.00