Ligand-gated Ion Channels
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N-(4-Hydroxyphenylacetyl)spermine
N-(4-Hydroxyphenylacetyl)spermine is a wasp toxin analog, which has been reported to be selective for NMDA receptors in mammalian CNS. Learn MoreStarting at: $125.00
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L-689,560
L-689,560 is a very potent antagonist at the glycine-NMDA site. Learn MoreStarting at: $135.00
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NS 1738
NS 1738 is a selective positive allosteric modulator of α7 nicotinic acetylcholine receptors. Exhibits no substantial activity for α4β2, α3β3 and α1-containing receptors. Learn MoreStarting at: $99.00
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Homoquinolinic acid
Homoquinolinic acid is a potent NMDA receptor agonist; subtype-selective. Learn MoreStarting at: $129.00
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(2R,3S)-Chlorpheg
(2R,3S)-Chlorpheg is a weakly active NMDA receptor antagonist. Learn MoreStarting at: $185.00
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CIQ
CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit, which increases channel opening efficiency and enhances NMDA receptor responses. Learn MoreStarting at: $119.00
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PHA 543613 hydrochloride
PHA 543613 hydrochloride is a potent α7 nAChR agonist that displays selectivity over α3β4, α1β1γδ, α4β2 and 5-HT3 receptors, which positively influences sensory gating and memory in in vivo models of schizophrenia. Learn MoreStarting at: $149.00
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L-701,324
L-701,324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. Learn MoreStarting at: $95.00
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DQP 1105
DQP 1105 is a noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC50 values are 2.7, 8.5, 121, 153, 198 and 206 μM respectively). Learn MoreStarting at: $119.00
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(±)-1-(1,2-Diphenylethyl)piperidine maleate
(±)-1-(1,2-Diphenylethyl)piperidine maleate is a high affinity antagonist at the ion channel on the NMDA receptor. Learn MoreStarting at: $85.00
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PHA 568487
PHA 568487 is an orally active and brain penetrant agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively). Learn MoreStarting at: $99.00
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(RS)-(Tetrazol-5-yl)glycine
(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA. Learn MoreStarting at: $140.00
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DL-AP5 Sodium salt
DL-AP5 Sodium salt is a sodium salt of DL-AP5. Potent NMDA antagonist. Learn MoreStarting at: $69.00
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5,7-Dichlorokynurenic acid
5,7-Dichlorokynurenic acid is a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine). Learn MoreStarting at: $65.00
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CCMQ
CCMQ is used in conjunction with [3H]-homoquinolinic acid to characterize NR2B-containing NMDA receptors which selectively inhibits [3H]-homoquinolinic acid binding to non-NMDA sensitive sites. Learn MoreStarting at: $95.00
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Pentamidine isethionate
Antimicrobial. Neuroprotective; inhibits constitutive nitric oxide synthase in the brain and acts as a NMDA glutamate receptor antagonist. Learn MoreStarting at: $80.00
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(R)-4-Carboxyphenylglycine
(R)-4-Carboxyphenylglycine is a Moderately potent NMDA receptor antagonist. Learn MoreStarting at: $135.00
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Phencyclidine hydrochloride
Phencyclidine hydrochloride is a non-competitive NMDA receptor antagonist and sigma receptor agonist. Learn MoreStarting at: $55.00
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L-Aspartic acid
L-Aspartic acid is an endogenous NMDA receptor agonist. Learn MoreStarting at: $32.00
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Glycine
Glycine acts as a modulator of excitatory amino acid transmission mediated by NMDA receptors. Learn MoreStarting at: $33.00