JAK Kinase

6 Item(s)

per page

  • Cucurbitacin I

    Cucurbitacin I is a selective inhibitor of STAT3/JAK2 signaling, which inhibits the activation of STAT3 and JAK2 and displays no activity on Src, Akt, ERK and JNK. Learn More

    Starting at: $169.00

    View Details

  • ZM 449829

    Potent is a selective inhibitor of Janus tyrosine kinase 3 (JAK3), which binds competitively to the JAK3 ATP site. And inhibits STAT-5 phosphorylation and T-cell proliferation. Learn More

    Starting at: $89.00

    View Details

  • TCS 21311

    TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM), which inhibits GSK-3β, PKCα and PKCθ (IC50 values are 3, 13 and 68 nM respectively). Learn More

    Starting at: $155.00

    View Details

  • 1,2,3,4,5,6-Hexabromocyclohexane

    1,2,3,4,5,6-Hexabromocyclohexane potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. Learn More

    Starting at: $75.00

    View Details

  • ZM 39923 hydrochloride

    ZM 39923 hydrochloride is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3) with pIC50 values of 7.1, 5.6, 4.4, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Learn More

    Starting at: $119.00

    View Details

  • NSC 33994

    NSC 33994 is a selective inhibitor of JAK2 with an IC50 value of 60 nM. Learn More

    Starting at: $139.00

    View Details

6 Item(s)

per page