Sphingosine-1-Phosphate Receptors

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  • CYM 5442 hydrochloride

    CYM 5442 hydrochloride is a potent and selective S1P1 agonist in vitro (EC50 = 1.35 nM), which induces acute lymphopenia in mice. Learn More

    Starting at: $135.00

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  • CS 2100

    CS 2100 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist with an EC50 value of 4.0 nM. Learn More

    Starting at: $169.00

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  • W146

    W146 is a potent sphingosine-1-phosphate receptor S1P1 selective antagonist that enhances capillary leakage and restores lymphocyte egress in vivo. Learn More

    Starting at: $109.00

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  • JTE 013

    JTE 013, a sphingosine-1-phosphate (S1P) receptor antagonist, inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. Learn More

    Starting at: $149.00

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  • VPC 23019

    VPC 23019 is a sphingosine-1-phosphate receptor antagonist, which inhibits S1P1 and S1P3 receptors (pKi values are 7.86 and 5.93 respectively). Learn More

    Starting at: $219.00

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  • Sphingosine-1-phosphate

    Sphingosine-1-phosphate endogenous second messenger involved in the control of cell proliferation and motility, and Ca2+ mobilization, which acts as an agonist at sphingosine-1-phosphate receptors (S1P1-5) and as an activator of GPR3, GPR6 and GPR12. Learn More

    Starting at: $119.00

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  • SEW 2871

    SEW 2871 is a novel, potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Learn More

    Starting at: $69.00

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  • CYM 50260

    CYM 50260 is a potent sphingosine-1-phosphate receptor 4 (S1P4) agonist (EC50 = 45 nM) which displays no activity at other S1P receptor subtypes (S1P1-3 and S1P5) at concentrations up to 25 μM. Learn More

    Starting at: $110.00

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  • CYM 50308

    CYM 50308 is a potent and selective sphingosine-1-phosphate receptor 4 (S1P4) agonist (EC50 values are 56 nM and 2100 nM for S1P4 and S1P5 receptors, respectively). Learn More

    Starting at: $150.00

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  • RP 001 hydrochloride

    RP 001 hydrochloride is a potent agonist of S1P1 receptors (EC50 = 9 pM), which induces internalization and polyubiquitination of S1P1 in vitro. Learn More

    Starting at: $155.00

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  • TC-SP 14

    TC-SP 14 is a potent and selective S1P1 agonist (EC50 values are 0.042 and 3.47 μM for human S1P1 and S1P3 respectively). Learn More

    Starting at: $135.00

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  • CYM 5541

    CYM 5541 is a selective sphingosine-1-phosphate receptor 3 (S1P3) allosteric agonist that occupies a different space within the ligand binding pocket of S1P3 than S1P. Learn More

    Starting at: $115.00

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12 Item(s)

per page