Cell Metabolism

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  • Tramiprosate

    Tramiprosate is a sulfated glycosaminoglycan (sGAG) mimetic that targets soluble amyloid β (Aβ) and maintains Aβ in a non-fibrillar form, which decreases Aβ42-induced neuronal death and inhibits amyloid deposition in vitro. Learn More

    Starting at: $49.00

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  • SMER 28

    SMER 28 is a positive regulator of autophagy in a mechanism independent from the mTOR pathway, which increases autophagosome synthesis and enhances clearance of model autophagy substrates such as mutant huntingtin and A53T α-synuclein, associated with Huntington's disease and Parkinson's disease, respectively. Learn More

    Starting at: $85.00

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  • Trovafloxacin mesylate

    Fluoroquinolone antibiotic. Inhibits bacterial DNA topoisomerase IV and DNA gyrase and forms a stable quinolone-DNA complex with these enzymes which reversibly inhibits DNA synthesis. Displays potent activity against gram-positive and gram-negative bacteria. Increases the production of mitochondrial NO in immortalized hepatocytes; also increases mitochondrial Ca2+. Learn More

    Starting at: $135.00

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  • 8-Chloroadenosine

    8-Chloroadenosine is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP, which incorporates into RNA during transcription and inhibits RNA synthesis and exhibits cytotoxicity in MM.1S, RPMI-8226 and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic catastrophe in A549 and H1299 cells. Learn More

    Starting at: $145.00

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  • Viomycin

    Viomycin is a member of the tuberactinomycin family of antibiotics, which inhibits group I intron splicing and prokaryotic protein synthesis. Learn More

    Starting at: $109.00

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  • Homoharringtonine

    Homoharringtonine is an inhibitor of protein synthesis which blocks elongation phase of translation by binding to the 60-S ribosome subunit. Learn More

    Starting at: $119.00

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  • (±)-Hexanoylcarnitine chloride

    (±)-Hexanoylcarnitine chloride is a homolog of acetylcarnitine chloride Learn More

    Starting at: $89.00

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  • Acipimox

    Acipimox is an antilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels. Learn More

    Starting at: $65.00

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  • (±)-Acetylcarnitine chloride

    (±)-Acetylcarnitine chloride is weak cholinergic agonist and important intermediates in lipid metabolism. Learn More

    Starting at: $49.00

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  • Fatostatin A

    Fatostatin A is an inhibitor of sterol regulatory element binding protein (SREBP); impairs the activation of SREBP-1 and SREBP-2. Learn More

    Starting at: $85.00

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  • (±)-Octanoylcarnitine chloride

    (±)-Octanoylcarnitine chloride is a homolog of acetylcarnitine chloride. Acylcarnitines are important intermediates in lipid metabolism. Learn More

    Starting at: $85.00

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  • (±)-Lauroylcarnitine chloride

    (±)-Lauroylcarnitine chloride is a homolog of acetylcarnitine chloride. Learn More

    Starting at: $85.00

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  • R 59022

    R 59022 is a diacylglycerol (DAG) kinase inhibitor with an IC50 value of 2.8 μM. Learn More

    Starting at: $105.00

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  • (±)-Decanoylcarnitine chloride

    (±)-Decanoylcarnitine chloride is a homolog of acetylcarnitine chloride . Learn More

    Starting at: $80.00

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  • (±)-Myristoylcarnitine chloride

    (±)-Myristoylcarnitine chloride is a homolog of acetylcarnitine chloride. Learn More

    Starting at: $80.00

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  • (±)-Propionylcarnitine chloride

    (±)-Propionylcarnitine chloride is the homolog of acetylcarnitine chloride. Learn More

    Starting at: $85.00

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  • TCS PrP Inhibitor 13

    TCS PrP Inhibitor 13 is an antiprion agent, which potently inhibits protease-resistant prion protein (PrP-res) accumulation in two types of prion-infected mouse neuroblastoma (N2a) cell lines (IC50 = 3 nM). Learn More

    Starting at: $105.00

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  • B2

    B2 Promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease, which prevents mutant huntingtin-mediated proteasome dysfunction and reduces α-synuclein-mediated toxicity. Learn More

    Starting at: $90.00

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  • CCCP

    CCCP is a widely used uncoupler of oxidative phosphorylation. Learn More

    Starting at: $89.00

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  • FCCP

    FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria. Learn More

    Starting at: $89.00

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20 Item(s)

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