Esterases
-
HA 130
HA 130 is a selective autotaxin inhibitor (IC50 = 28 nM), which binds and inhibits autotaxin reversibly. Learn MoreStarting at: $135.00
-
S 32826
S 32826 is an inhibitor of autotaxin (IC50 = 9 nM), which displays similar inhibitory effects at all three autotaxin isoforms (α, β and γ)and inhibits LPA release from adipocytes (IC50 = 90 nM). Learn MoreStarting at: $135.00
-
Pristimerin
Pristimerin is a potent and reversible inhibitor of monoacylglycerol lipase (MGL) (IC50 = 93 nM), which displays antitumor, anti-inflammatory and antimicrobial activities. Learn MoreStarting at: $135.00
-
GSK 264220A
GSK 264220A is an endothelial lipase and lipoprotein lipase inhibitor with IC50 values of 0.13 and 0.10 μM respectively. Learn MoreStarting at: $119.00
-
RHC 80267
RHC 80267 is an inhibitor of diacylglycerol lipase that potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity. Learn MoreStarting at: $99.00
-
Tacrine hydrochloride
AIDA is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a), having no effect on group II (mGlu2) or group III (mGlu4) receptors expressed individually in baby hamster kidney cells. Learn MoreStarting at: $60.00
-
Ambenonium dichloride
Ambenonium dichloride is a extremely potent, selective and rapidly reversible inhibitor of acetylcholinesterase (AChE) with IC50 values =0.000698 and 8.20 μM at AChE and BChE respectively. Learn MoreStarting at: $99.00
-
Acephate
Anticholinesterase insecticide that produces cholinotoxicity, which displays weak inhibition of rat acetylcholinesterase (AChE) but potently inhibits cockroach AChE. Learn MoreStarting at: $59.00
-
Physostigmine hemisulfate
Physostigmine hemisulfate is a cholinesterase inhibitor. Learn MoreStarting at: $33.00
-
Galanthamine hydrobromide
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Learn MoreStarting at: $75.00
-
Rivastigmine tartrate
Rivastigmine tartrate is a dual cholinesterase inhibitor (ChEI) which inhibits both butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). Learn MoreStarting at: $70.00
-
PE 154
PE 154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 values are 280 pM and 16 nM respectively), which targets and labels β-amyloid plaques in histochemical analysis. Learn MoreStarting at: $160.00
-
Phenserine
Phenserine is a Physostigmine analog that inhibits acetylcholinesterase.Phenserin also inhibits production of amyloid precursor protein (APP) and A&beta and improves morris water maze performance of scopolamine-treated rats. Learn MoreStarting at: $95.00
-
STF 083010
STF 083010 is an inhibitor of IRE1α endonuclease activity; blocks endogenous XBP1 mRNA splicing. Learn MoreStarting at: $119.00
-
Edelfosine
Edelfosine is a synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C. Learn MoreStarting at: $89.00
-
LY 311727
AM 630 is a CB2 antagonist/inverse agonist (Ki = 31.2 nM) that displays 165-fold selectivity over CB1 receptors. Learn MoreStarting at: $140.00
-
o-3M3FBS
o-3M3FBS is an inactive analog of m-3M3FBS. Used as a negative control. Learn MoreStarting at: $99.00
-
OBAA
OBAA is a potent inhibitor of phospholipase A2 (IC50 = 70 nM), which reduces bronchospasm in guinea pigs in vivo. Learn MoreStarting at: $90.00
-
m-3M3FBS
m-3M3FBS is a activator of phospholipase C (PLC), which stimulates superoxide generation, Ca2+ release and inositol phosphate formation in a variety of cell types, and inhibits growth of the leukemic cell lines U937 and THP-1. Learn MoreStarting at: $98.00
-
AACOCF3
AACOCF3 is an inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Learn MoreStarting at: $65.00