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Polymerases
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NU 1025
NU 1025 is a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). Learn MoreStarting at: $105.00
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BYK 204165
BYK 204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively). Learn MoreStarting at: $95.00
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EB 47
EB 47 is a potent inhibitor of PARP-1 (IC50 = 45 nM), which reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model. Learn MoreStarting at: $145.00
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TC-E 5001
TC-E 5001 is a dual tankyrase (TNKS) inhibitor that inhibits wnt signaling and stabilizes Axin2 levels. Learn MoreStarting at: $99.00
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DR 2313
DR 2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Learn MoreStarting at: $49.00
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4-HQN
4-HQN is an inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 = 9.5 μM), which displays mixed inhibition with respect to NAD+. Protective against ischemia-reperfusion induced ROS production, and subsequent mitochondrial and cell damage in rat heart. Learn MoreStarting at: $69.00
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BYK 49187
Chromanol 293B is a blocker of the slow delayed rectifier K+ current (IKs) (IC50 = 1-10 μM), which blocks the CFTR chloride current (ICFTR) (IC50 = 19 μM). Learn MoreStarting at: $70.00
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Acyclovir
Acyclovir, an antiviral agent, is active against herpes simplex viruses HSV-1 and HSV-2 with EC50 values of 0.85 and 0.86 μM respectively. Learn MoreStarting at: $59.00
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Thiolutin
Thiolutin is Antibiotic, inhibits bacterial RNA polymerase, Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and suppresses tumor cell-induced angiogenesis. Learn MoreStarting at: $99.00
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Mithramycin A
Mithramycin A is an anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Learn MoreStarting at: $75.00
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TMPyP4 tosylate
Cationic porphyrin; inhibits human telomerase. Stacks with G tetrads to stabilize quadruplex DNA, which inhibits cell proliferation and induces cell death in three myeloma cell lines. Learn MoreStarting at: $79.00
