Kainate Receptors
-
ATPA
ATPA is a selective and potent GluR5 kainate receptor agonist (Ki = 4.3 nM), inactive at GluR6 (Ki > 1 mM) and only weakly active at AMPA receptors (GluR1-4) and the kainate receptors KA-2 and GluR7 (Ki values of 6 - 14 μM). Learn MoreStarting at: $140.00
-
UBP 310
UBP 310 is a GLUK5 kainate receptor antagonist that also blocks recombinant homomeric GLUK7 receptors and displays 12,700-fold selectivity for GLUK5 over GLUK6. Learn MoreStarting at: $109.00
-
UBP 302
UBP 302, an active enantiomer of UBP 296, is a selective and potent GLUK5 (GluR5)-subunit containing kainate receptor antagonist that displays ~ 260-fold selectivity over AMPA receptors and ~ 90-fold selectivity over recombinant human GLUK6- and GLUK2-containing kainate receptors. Learn MoreStarting at: $195.00
-
UBP 296
UBP 296 is a selective GluR5-subunit containing kainate receptor antagonist that displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Learn MoreStarting at: $149.00
-
NS 3763
NS 3763 is a selective non-competitive kainate receptor antagonist that displays selectivity for GLUK5 subunit-containing receptors with IC50 values of 1.6 and > 30 μM for homomeric GLUK5 and GLUK6 receptors respectively. Learn MoreStarting at: $99.00
-
UBP 301
UBP 301 is a potent kainate receptor antagonist that displays ~ 30-fold selectivity over AMPA receptors. Learn MoreStarting at: $139.00
-
Kainic acid
Kainic acid is a selective agonist at kainate receptors. Potent excitant and neurotoxin. Learn MoreStarting at: $65.00
-
SYM 2081
SYM 2081 is a potent and highly selective kainate receptor agonist, with an IC50 for inhibition of [3H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Learn MoreStarting at: $139.00
-
Domoic acid
Domoic acid is more potent and possibly more selective than kainate at kainate receptors, as demonstrated in electrophysiological studies. Learn MoreStarting at: $110.00
-
(S)-(-)-5-Iodowillardiine
(S)-(-)-5-Iodowillardiine demonstrates high affinity for the kainate receptor subtype hGluR5 (Ki = 0.24 nM) and 600-4000-fold selectivity over both the AMPA receptor subtypes and the homomeric kainate receptor hGluR6. Learn MoreStarting at: $135.00
-
ACET
ACET is a potent and selective GluR5-containing kainate receptor antagonist that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Learn MoreStarting at: $275.00