NOP Receptors

(±)-J 113397

(±)-J 113397 is a potent and selective NOP receptor antagonist (IC50 values are 2.3, 1400, 2200 and > 10000 nM for NOP, κ, μ and δ-opioid receptors respectively), which inhibits nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test. Learn More

Starting at: $189.00

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NNC 63-0532

NNC 63-0532 is a potent non-peptide agonist for the NOP receptor (EC50 = 305 nM, Ki = 7.3 nM); ~ 12-fold selective over other receptors. Learn More

Starting at: $155.00

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SCH 221510

SCH 221510 is a potent and selective nociceptin opioid receptor (NOP) agonist (EC50 values are 12, 693, 683 and 8071 nM, and Ki values are 0.3, 65, 131 and 2854 nM at NOP, μ-, κ- and δ-opioid receptors respectively). Learn More

Starting at: $145.00

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SB 612111 hydrochloride

SB 612111 hydrochloride is a selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively), which antagonizes the pronociceptive action of nociceptin in an acute pain model. Learn More

Starting at: $179.00

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Trap 101

Trap 101 is a potent and selective nociceptin/orphanin FQ (NOP) receptor antagonist. Learn More

Starting at: $139.00

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