Adrenergic α1 Receptors
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Tamsulosin hydrochloride
Tamsulosin hydrochloride is a selective α1A-adrenoceptor antagonist (pKi values are 9.97, 9.64 and 8.86 for α1A, α1B and α1D subtypes respectively). Learn MoreStarting at: $110.00
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Urapidil hydrochloride
Urapidil hydrochloride is an α1-adrenoceptor antagonist and 5-HT1A receptor agonist. Learn MoreStarting at: $99.00
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Terazosin hydrochloride
Terazosin hydrochloride is an α1- and α2B-adrenoceptor antagonist with Ki values of 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively. Learn MoreStarting at: $70.00
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(R)-(-)-Phenylephrine hydrochloride
(R)-(-)-Phenylephrine hydrochloride is an α1-adrenoceptor agonist. Learn MoreStarting at: $49.00
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WB 4101 hydrochloride
WB 4101 hydrochloride is an α1A-adrenergic selective antagonist. Learn MoreStarting at: $89.00
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RS 17053 hydrochloride
Ro 60-0175 fumarate is a potent, selective 5-HT2 receptor agonist; shows selectivity for the 5-HT2C subtype (pKi values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). Learn MoreStarting at: $95.00
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Cirazoline hydrochloride
Cirazoline hydrochloride is a selective α1 agonist. Learn MoreStarting at: $90.00
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RS 100329 hydrochloride
RS 100329 hydrochloride is a subtype-selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors), which displays 126- and 50-fold selectivity over human α1B and α1D receptors respectively. Active in vivo. Learn MoreStarting at: $119.00
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AH 11110 hydrochloride
AH 11110 hydrochloride is a subtype-selective ligand for the α1B-adrenoceptor. Learn MoreStarting at: $110.00
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Rec 15/2615 dihydrochloride
Rec 15/2615 dihydrochlorideelective is a α1B-adrenoceptor antagonist (Ki values are 0.3, 1.9 and 2.6 nM at human α1B, α1A and α1D receptors respectively). Learn MoreStarting at: $110.00
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SNAP 5089
SNAP 5089 is a subtype-selective α1A-adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (Kivalues are 0.35, 220, 370, 540, 800 and 1200 nM for α1A, α1B, α2C, α1D, α2B and α2A subtypes respectively and 540 nM for L-type Ca2+ channels), which inhibits noradrenalin-induced contractions in rabbit vascular and lower urinary tissues. Learn MoreStarting at: $105.00
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2-MPMDQ
2-MPMDQ is a potent and selective α1-adrenoceptor antagonist; hypotensive. Learn MoreStarting at: $95.00
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2-PMDQ
2-PMDQ is a potent and selective α1-adrenoceptor antagonist and antihypertensive. Learn MoreStarting at: $105.00
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3-MPPI
3-MPPI is a very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM) which displays different binding properties for each α1 subtype (pKi values are 8.74, 9.44 and 9.57 for α1B, α1D and α1A adrenoceptors respectively). Learn MoreStarting at: $100.00
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(S)-(+)-Niguldipine hydrochloride
(S)-(+)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist; more active enantiomer. Learn MoreStarting at: $110.00
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(R)-(-)-Niguldipine hydrochloride
(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist; less active enantiomer. Learn MoreStarting at: $110.00
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A 61603 hydrobromide
A 61603 hydrobromide is a potent α-adrenoceptor agonist that is at least 35-fold more potent at α1A than at α1B or α1D sites. Learn MoreStarting at: $105.00
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Alfuzosin hydrochloride
Alfuzosin hydrochloride is a uro-selective α1 adrenoceptor antagonist that inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Learn MoreStarting at: $69.00