7-TM Receptors
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SHA 68
SHA 68 is a selective neuropeptide S receptor (NPSR) antagonist with IC50 values of 22.0 and 23.8 nM for human NPSR Asn107 and Ile107 variants respectively. Learn MoreStarting at: $139.00
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NF 340
NF 340 is a P2Y11 antagonist which exhibits 520-fold selectivity for P2Y11 over P2Y1, P2Y2, P2Y4, P2Y6 and P2Y12 receptors, and displays competitive antagonism against ATPγS (pIC50 values are 6.43 and 7.14 in Ca2+ and cAMP assays respectively). Learn MoreStarting at: $140.00
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MRS 2690
MRS 2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose. Learn MoreStarting at: $220.00
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AR-C 66096 tetrasodium salt
AR-C 66096 tetrasodium salt is a potent and selective P2Y12 receptor antagonist which blocks ADP-induced inhibition of adenylyl cyclase in vitro (pKB =7.6) and inhibits ADP-induced aggregation of washed human platelets (pIC50 = 8.16). Learn MoreStarting at: $225.00
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MRS 4062 triethylammonium salt
MRS 4062 triethylammonium salt is a selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively). Learn MoreStarting at: $180.00
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UTPγS trisodium salt
UTPγS trisodium salt is a selective P2Y2 and P2Y4 receptor agonist. Enzymatically stable. Learn MoreStarting at: $140.00
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MRS 2957 triethylammonium salt
MRS 2957 triethylammonium salt is a potent P2Y6 agonist (EC50 = 12 nM). Displays 14- and 66-fold selectivity against P2Y2 and P2Y4 receptors respectively. Learn MoreStarting at: $199.00
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5-OMe-UDP trisodium salt
5-OMe-UDP trisodium salt is a potent P2Y6 agonist (EC50 = 0.08 μM) which displays greater potency at P2Y6 than UDP. Learn MoreStarting at: $145.00
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PSB 0739
PSB 0739 is a highly potent P2Y12 receptor antagonist (Ki = 24.9 nM). Learn MoreStarting at: $125.00
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MRS 2768 tetrasodium salt
MRS 2768 tetrasodium salt is a selective P2Y2 agonist (EC50 = 1.89 μM). Learn MoreStarting at: $195.00
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MRS 2179 tetrasodium salt
MRS 2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors (KB = 100 nM). Learn MoreStarting at: $145.00
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NF 546
NF 546 is a P2Y11 agonist (pEC50 = 6.27). Exhibits selectivity for P2Y11 over a range of P2Y and P2X receptors. Learn MoreStarting at: $149.00
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UDP disodium salt
UDP disodium salt endogenous P2Y receptor agonist which preferentially activates P2Y6, which is shown to be a competitive antagonist at P2Y14 receptors. Learn MoreStarting at: $49.00
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2-Methylthioadenosine diphosphate trisodium salt
2-Methylthioadenosine diphosphate trisodium salt is a potent purinergic agonist displaying selectivity for P2Y1, P2Y12 and P2Y13 receptors (pEC50 = 8.29 and 9.05 for P2Y1 and P2Y12, EC50 = 19 nM for P2Y13), which induces aggregation of, and inhibits cAMP accumulation in, platelets in vitro. Learn MoreStarting at: $219.00
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2-ThioUTP tetrasodium salt
2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 values are 0.035, 0.35 and 1.5 μM for hP2Y2, hP2Y4 and hP2Y6 receptors respectively). Learn MoreStarting at: $269.00
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Anti-PIKFyve
Anti-PIKFyve is an antibody raised against recombinant protein corresponding to amino acid residues 1083-1200 of human PIKfyve . Learn MoreStarting at: $299.00
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MRS 2211
MRS 2211 is a competitive P2Y13 receptor antagonist (pIC50 = 5.97) that displays > 20-fold selectivity over P2Y1 and P2Y12 receptors. Learn MoreStarting at: $89.00
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ATP disodium salt
ATP disodium salt is a P2 purinoceptor agonist. Learn MoreStarting at: $59.00
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PSB 0474
PSB 0474 is a potent and selective P2Y6 receptor agonist. Learn MoreStarting at: $229.00
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MRS 2693 trisodium salt
MRS 2693 trisodium salt is a selective P2Y6 agonist with an EC50 value of 0.015 μM at the hP2Y6 receptor. Learn MoreStarting at: $179.00