Page 6 | 5-HT Receptors - 7-TM Receptors

SB 258719 hydrochloride

SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist that displays > 100-fold selectivity over a range of other receptors. Learn More

Starting at: $119.00

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LP 20 hydrochloride is a ligand of the 5-HT7 receptor (Ki = 2.6 nM) which exhibits agonist and antagonist activity. It also displays selectivity over adrenergic α1 and 5-HT1A receptors (Ki values are 156 and 476 nM respectively). Learn More

Starting at: $115.00

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LP 12 hydrochloride

LP 12 hydrochloride is a 5-HT7 receptor agonist displaying selectivity over D2, 5-HT1A and 5-HT2A receptors (Ki values are 0.22, 7.3, 52.7 and 326 nM respectively), which induces relaxation of substance P-induced contractions in guinea pig ileum (EC50 = 1.77 μM). Learn More

Starting at: $135.00

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AS 19

AS 19 is a potent 5-HT7 receptor agonist (IC50 = 0.83 nM), that enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo. Learn More

Starting at: $109.00

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Methiothepin maleate

Methiothepin maleate is a potent 5-HT2 antagonist, also active as 5-HT1 antagonist, which displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively). Learn More

Starting at: $65.00

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Serotonin hydrochloride

Serotonin hydrochloride is an Endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Learn More

Starting at: $60.00

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LY 215840

LY 215840 is a 5-HT2/5-HT7 receptor antagonist which reduces stimulatory effect of serotonin on aldosterone secretion and 5-HT-induced cAMP formation (pKB = 8.26). Learn More

Starting at: $135.00

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