5-HT Receptors

Items 81 to 100 of 111 total

per page

Page:
  1. 2
  2. 3
  3. 4
  4. 5
  5. 6
  • L-703,664 succinate

    L-703,664 succinate is a 5-HT1D receptor agonist that displays selectivity over other 5-HT receptor subtypes (pIC50 values are 7.2, 6.1, < 5.0 and < 5.0 for 5-HT1D, 5-HT1A, 5-HT2A and 5-HT3 respectively) and other receptors (pIC50 < 5.0 for adenosine, adrenergic, excitatory amino acids, dopamine, histamine, muscarinic, nicotinic and opiate receptors). Learn More

    Starting at: $140.00

    View Details

  • SDZ SER 082 fumarate

    SDZ SER 082 fumarate is a selective 5-HT2B/2C receptor antagonist with low affinity for 5-HT1A receptors which inhibits [3H]-mesulergine binding to 5-HT2C receptors with a pKD of 7.8, and Inhibits 5-HT2B mediated responses in the rat fundus (pKB = 7.34). Learn More

    Starting at: $135.00

    View Details

  • L-694,247

    L-694,247 is a selective and extremely potent 5-HT1D receptor agonist. Learn More

    Starting at: $135.00

    View Details

  • BRL 54443

    BRL 54443 acts as a selective agonist for the 5-HT1E and 5-HT1F serotonin receptor subtypes with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors. Learn More

    Starting at: $92.00

    View Details

  • SB 699551

    SB 699551 is a selective 5-ht5a receptor antagonist. Learn More

    Starting at: $145.00

    View Details

  • LY 344864 hydrochloride

    LY 344864 hydrochloride is a potent, selective 5-HT1F receptor agonist (EC50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μM for 5-HT1F, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT2B, 5-HT2C, 5-HT2A and 5-HT7 receptors respectively). Learn More

    Starting at: $130.00

    View Details

  • LY 334370 hydrochloride

    LY 334370 hydrochloride is a selective 5-HT1F receptor agonist (Ki values are 1.87, 16.4, > 100 (IC50), 176, 189, 281, 1280, 1530, 1550, > 3000 (IC50) and 3250 nM for 5-HT1F, 5-HT1A, 5-HT4, 5-HT1E, 5-HT1B, 5-HT1D, 5-HT2B, 5-HT2A, 5-HT7, 5-HT6 and 5-HT2C receptors respectively). Learn More

    Starting at: $140.00

    View Details

  • WAY 208466 dihydrochloride

    WAY 208466 dihydrochloride is a high affinity, selective 5-HT6 agonist with antidepressant and anxiolytic-like effects. Learn More

    Starting at: $149.00

    View Details

  • EMD 386088 hydrochloride

    EMD 386088 hydrochloride is a potent 5-HT6 receptor agonist (EC50 = 1.0 nM) that displays selectivity over other 5-HT receptors (IC50 values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6, 5-HT1D, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT4, 5-HT1A and 5-HT7 receptors respectively). Learn More

    Starting at: $99.00

    View Details

  • SGS 518 oxalate

    SGS 518 oxalate is a selective antagonist of the 5-HT6 subtype of the serotonin receptor. Learn More

    Starting at: $139.00

    View Details

  • NPS ALX Compound 4a dihydrochloride

    NPS ALX Compound 4a dihydrochloride is a potent and competitive 5-HT6 antagonist (IC50 = 7.2 nM, Ki = 0.2 nM) that displays selectivity over other 5-HT and D2 receptors. Learn More

    Starting at: $139.00

    View Details

  • EMDT oxalate

    EMDT oxalate is a selective 5-HT6 agonist (with a Ki value of 16 nM at human 5-HT6 receptors) which exhibits potency comparable to serotonin for the activation of adenylate cyclase, and displays antidepressant-like effects. Learn More

    Starting at: $119.00

    View Details

  • MS 245 oxalate

    MS 245 oxalate is a high affinity 5-HT6 antagonist (Ki = 2.1 nM), which potentiates the hypolocomotor actions of (-)-nicotine in mice. Learn More

    Starting at: $139.00

    View Details

  • SB 271046 hydrochloride

    SB 271046 hydrochloride is an orally active, selective 5-HT6 antagonist (pKi values are 9.02-8.92, 6.55, 6.35, 6.27, 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT6, 5-HT1D, 5-HT1A, D3, 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. Learn More

    Starting at: $140.00

    View Details

  • Ro 04-6790

    Ro 04-6790 is a potent and selective 5-HT6 receptor antagonist (pKi values are 7.26 and 7.35 at rat and human 5-HT6 receptors respectively), which displays no affinity at a range of other receptors (IC50 > 10 μM). Learn More

    Starting at: $110.00

    View Details

  • BGC 20-761

    BGC 20-761 is a selective, high affinity 5-HT6 antagonist (Ki = 20 nM). Learn More

    Starting at: $110.00

    View Details

  • ST 1936 oxalate

    ST 1936 oxalate is a high affinity, selective agonist of 5-HT6 receptors (Ki values are 13, 168, and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors respectively). Learn More

    Starting at: $110.00

    View Details

  • 5-Carboxamidotryptamine maleate

    5-Carboxamidotryptamine maleate is a 5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B , 5-HT1D, 5-ht5 and 5-HT7 receptors. Learn More

    Starting at: $139.00

    View Details

  • LP 44

    LP 44 is a high affinity 5-HT7 receptor agonist that displays selectivity over 5-HT1A and 5-HT2A receptors (200- and > 1000-fold respectively). Learn More

    Starting at: $145.00

    View Details

  • SB 269970 hydrochloride

    SB 269970 hydrochloride is a potent and selective 5-HT7 receptor antagonist (pKi values are 8.9, 7.2 and 6.0 for 5-HT7A, 5-HT5A and 5-HT1B and < 6.0 for 5-HT1A, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT4 and 5-HT6 receptors respectively). Learn More

    Starting at: $135.00

    View Details

Items 81 to 100 of 111 total

per page

Page:
  1. 2
  2. 3
  3. 4
  4. 5
  5. 6