5-HT2B Receptors

SDZ SER 082 fumarate

SDZ SER 082 fumarate is a selective 5-HT2B/2C receptor antagonist with low affinity for 5-HT1A receptors which inhibits [3H]-mesulergine binding to 5-HT2C receptors with a pKD of 7.8, and Inhibits 5-HT2B mediated responses in the rat fundus (pKB = 7.34). Learn More

Starting at: $135.00

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SB 204741

SB 204741 is a potent and selective 5-HT2B receptor antagonist (pA2 = 7.95) which displays ≥ 135-fold selectivity over 5-HT2C (pKi = 5.82), 5-HT2A (pKi < 5.2), 5-HT1A, 1D, 1E, 5-HT3 and 5-HT4 receptors. Learn More

Starting at: $115.00

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LY 272015 hydrochloride

LY 272015 hydrochloride is a high affinity 5-HT2B receptor antagonist that displays selectivity over 5-HT2A and 5-HT2C receptors (Ki values are 0.75, 21.63 and 28.7 nM for 5-HT2B, 5-HT2C and 5-HT2A receptors respectively). Learn More

Starting at: $135.00

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LY 266097 hydrochloride

LY 266097 hydrochloride is a selective 5-HT2B receptor antagonist (pKi = 9.3). Learn More

Starting at: $135.00

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α-Methyl-5-hydroxytryptamine maleate

α-Methyl-5-hydroxytryptamine maleate is a 5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B, 5-HT2A and 5-HT2C receptors respectively. Learn More

Starting at: $75.00

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BW 723C86 hydrochloride

DMP 543 is a K+ channel blocker and acetylcholine release stimulator, which potently enhances K+-stimulated [3H]-ACh release from rat hippocampal slices (EC50 = 700 nM), and also increases release of dopamine and glutamate (EC50 values are 0.25 and 0.22 μM, respectively). Learn More

Starting at: $95.00

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m-CPP hydrochloride

m-CPP hydrochloride is a 5-HT2C/2B receptor agonist/partial agonist with pEC50 values of 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT2C, 2B and 2A, bovine 5-HT1A and rat 5-HT1B receptors respectively. Learn More

Starting at: $38.00

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