Polymerases

11 Item(s)

per page

  • NU 1025

    NU 1025 is a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). Learn More

    Starting at: $105.00

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  • BYK 204165

    BYK 204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively). Learn More

    Starting at: $95.00

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  • EB 47

    EB 47 is a potent inhibitor of PARP-1 (IC50 = 45 nM), which reduces infarct volume in both a rat transient middle cerebral arterial occlusion model and a cardiac reperfusion model. Learn More

    Starting at: $145.00

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  • TC-E 5001

    TC-E 5001 is a dual tankyrase (TNKS) inhibitor that inhibits wnt signaling and stabilizes Axin2 levels. Learn More

    Starting at: $99.00

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  • DR 2313

    DR 2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Learn More

    Starting at: $49.00

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  • 4-HQN

    4-HQN is an inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 = 9.5 μM), which displays mixed inhibition with respect to NAD+. Protective against ischemia-reperfusion induced ROS production, and subsequent mitochondrial and cell damage in rat heart. Learn More

    Starting at: $69.00

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  • BYK 49187

    Chromanol 293B is a blocker of the slow delayed rectifier K+ current (IKs) (IC50 = 1-10 μM), which blocks the CFTR chloride current (ICFTR) (IC50 = 19 μM). Learn More

    Starting at: $70.00

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  • Acyclovir

    Acyclovir, an antiviral agent, is active against herpes simplex viruses HSV-1 and HSV-2 with EC50 values of 0.85 and 0.86 μM respectively. Learn More

    Starting at: $59.00

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  • Thiolutin

    Thiolutin is Antibiotic, inhibits bacterial RNA polymerase, Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and suppresses tumor cell-induced angiogenesis. Learn More

    Starting at: $99.00

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  • Mithramycin A

    Mithramycin A is an anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Learn More

    Starting at: $75.00

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  • TMPyP4 tosylate

    Cationic porphyrin; inhibits human telomerase. Stacks with G tetrads to stabilize quadruplex DNA, which inhibits cell proliferation and induces cell death in three myeloma cell lines. Learn More

    Starting at: $79.00

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11 Item(s)

per page