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Signal Transduction
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BTZO 1
BTZO 1 is a macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM), which activates antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro. Learn MoreStarting at: $95.00
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Cardionogen 1
Cardionogen 1, a wnt signaling modulator, potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos and Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation. Learn MoreStarting at: $139.00
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W-5 hydrochloride
W-5 hydrochloride is a Calmodulin antagonist that inhibits Ca2+-calmodulin dependent PDE with an IC50 of 240 μM. Learn MoreStarting at: $99.00
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W-7 hydrochloride
W-7 hydrochloride is a calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase. Learn MoreStarting at: $99.00
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iCRT 14
iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) with IC50 of 40.3 nM in assays of Wnt pathway activity. Learn MoreStarting at: $139.00
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W-9 hydrochloride
W-9 hydrochloride is a Calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 72 μM. Learn MoreStarting at: $109.00
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cAMPS-Sp, triethylammonium salt
cAMPS-Sp, triethylammonium salt is a cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Learn MoreStarting at: $99.00
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cAMPS-Rp, triethylammonium salt
cAMPS-Rp, triethylammonium salt is a cell-permeable cAMP analog that acts as a competitive antagonist of cAMP-induced activation of PKA by interacting with cAMP binding sites on the regulatory subunits. Learn MoreStarting at: $99.00
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L-Arginine
L-Arginine is a precursor in the formation of nitric oxide. Learn MoreStarting at: $49.00
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CID 5951923
CID 5951923 is an inhibitor of Krüppel-like factor 5 (KLF5) transcription factor. Learn MoreStarting at: $149.00
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8-Bromo-cAMP (sodium salt)
8-Bromo-cAMP(sodium salt) is a cell-permeable cAMP analog and activator of protein kinase A. Learn MoreStarting at: $59.00
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SNAP
SNAP is a stable analog of endogenous S-nitroso compounds. Learn MoreStarting at: $59.00
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A-7 hydrochloride
A-7 hydrochloride is a potent calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Learn MoreStarting at: $89.00
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ICG 001
ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription that inhibits β-catenin/CBP interaction. Learn MoreStarting at: $99.00
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W-13 hydrochloride
W-13 hydrochloride is a calmodulin antagonist that inhibits calmodulin activated PDE activity with an IC50 of 68 μM. Learn MoreStarting at: $99.00
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BI 6015
BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that exhibits cytotoxic activity in a range of tumor cell lines, including human hepatocellular carcinoma. Learn MoreStarting at: $129.00
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SNOG
SNOG is a carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation. Learn MoreStarting at: $59.00
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Calmidazolium chloride
Calmidazolium chloride is a calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 μM respectively. Learn MoreStarting at: $99.00
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AS 101
AS 101 is a immunomodulator which inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release. Learn MoreStarting at: $80.00
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CGS 9343B
CGS 9343B is a Calmodulin antagonist whcih inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50 of 3.3 nM. Learn MoreStarting at: $135.00
