Signal Transduction
-
BTZO 1
BTZO 1 is a macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM), which activates antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro. Learn MoreStarting at: $95.00
-
W-5 hydrochloride
W-5 hydrochloride is a Calmodulin antagonist that inhibits Ca2+-calmodulin dependent PDE with an IC50 of 240 μM. Learn MoreStarting at: $99.00
-
Cardionogen 1
Cardionogen 1, a wnt signaling modulator, potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos and Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation. Learn MoreStarting at: $139.00
-
SNOG
SNOG is a carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation. Learn MoreStarting at: $59.00
-
Calmidazolium chloride
Calmidazolium chloride is a calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 μM respectively. Learn MoreStarting at: $99.00
-
Pirfenidone
Pirfenidone is a antifibrotic agent, effective in models of pulmonary and lung fibrosis that regulates cytokine levels following oral administration in vivo. Learn MoreStarting at: $89.00
-
STO-609 acetate
STO-609 acetate is a selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase. The Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively. Learn MoreStarting at: $69.00
-
Dibutyryl-cAMP, sodium salt
LY 333531 hydrochloride is an isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src). Learn MoreStarting at: $55.00
-
SIN-1 chloride
ZK 200775 is a competitive AMPA/kainate antagonist. Learn MoreStarting at: $98.00
-
Bropirimine
Bropirimine, an Immunomodulatory and antitumor compound, induces interferon (IFN)-α/β production and augments natural killer (NK) cell activity. Orally active. Learn MoreStarting at: $93.00
-
4-IPP
4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF), which acts as a suicide substrate to inactivate MIF catalytic and biological functions; inhibits MIF-associated liver enzyme activity in vivo. Learn MoreStarting at: $105.00
-
W-7 hydrochloride
W-7 hydrochloride is a calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase. Learn MoreStarting at: $99.00
-
iCRT 14
iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) with IC50 of 40.3 nM in assays of Wnt pathway activity. Learn MoreStarting at: $139.00
-
BI 6015
BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that exhibits cytotoxic activity in a range of tumor cell lines, including human hepatocellular carcinoma. Learn MoreStarting at: $129.00
-
W-13 hydrochloride
W-13 hydrochloride is a calmodulin antagonist that inhibits calmodulin activated PDE activity with an IC50 of 68 μM. Learn MoreStarting at: $99.00
-
A-7 hydrochloride
A-7 hydrochloride is a potent calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Learn MoreStarting at: $89.00
-
SNAP
SNAP is a stable analog of endogenous S-nitroso compounds. Learn MoreStarting at: $59.00
-
8-Bromo-cAMP (sodium salt)
8-Bromo-cAMP(sodium salt) is a cell-permeable cAMP analog and activator of protein kinase A. Learn MoreStarting at: $59.00
-
CID 5951923
CID 5951923 is an inhibitor of Krüppel-like factor 5 (KLF5) transcription factor. Learn MoreStarting at: $149.00
-
L-Arginine
L-Arginine is a precursor in the formation of nitric oxide. Learn MoreStarting at: $49.00