Cytoskeleton

18 Item(s)

per page

  • SMIFH2

    SMIFH2 is an inhibitor of formin homology 2 (FH2) domains, which prevents formin-mediated actin nucleation and barbed end elongation. Learn More

    Starting at: $89.00

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  • Jasplakinolide

    Jasplakinolide Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro.It also induces polymerization of actin monomers into F-actin in vivo. Learn More

    Starting at: $205.00

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  • Latrunculin A

    Latrunculin A is a reversible inhibitor of actin assembly that blocks actin adenine nucleotide exchange. Learn More

    Starting at: $119.00

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  • CK 666

    CK 666 is an inhibitor of the Arp2/3 complex, which inhibits actin polymerization (IC50 = 4 μM). Learn More

    Starting at: $119.00

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  • Cytochalasin D

    Cytochalasin D is a potent disruptor of actin filament function. Learn More

    Starting at: $75.00

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  • CK 869

    CK 869 is an inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex, which inhibits actin polymerization (IC50= 11 μM). Learn More

    Starting at: $119.00

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  • K 858

    K 858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor that induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells with a IC50 value of 1.3 μM. Learn More

    Starting at: $99.00

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  • Paprotrain

    Paprotrain, MKlp2 inhibitor, affects polar body extrusion during mouse oocyte maturation. Learn More

    Starting at: $52.00

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  • S-Trityl-L-cysteine

    S-Trityl-L-cysteine is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50 = 1 mM) and microtubule-activated ATPase activity of Eg5 (IC50 = 140 nM). Learn More

    Starting at: $65.00

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  • Monastrol

    Monastrol is a potent, cell-permeable, small molecule mitosis inhibitor that does not interact with tubulin. Learn More

    Starting at: $119.00

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  • UA 62784

    UA 62784 is an inhibitor of microtubule polymerization in vitro, which interacts with tubulin dimers and promotes the accumulation of mammalian cells in apoptosis. Learn More

    Starting at: $139.00

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  • Indibulin

    Indibulin is a microtubule destabilizer that blocks tubulin polymerization (IC50 = 0.3 μM). Learn More

    Starting at: $105.00

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  • Flutax 1

    Flutax 1 is a fluorescent taxol derivative that binds to the taxol microtubule binding site with high affinity (Ka ~ 107M-1). Learn More

    Starting at: $149.00

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  • Vinblastine sulfate

    Vinblastine sulfate is an anticancer agent; microtubule disrupter which induces apoptosis in cultured hepatocytes and human lymphoma cells. Learn More

    Starting at: $80.00

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  • D-64131

    D-64131 is a novel inhibitor of tubulin polymerization that inhibits tumor cell proliferation in vitro with an IC50 value of 74 nM. Learn More

    Starting at: $109.00

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  • Noscapine hydrochloride

    Noscapine hydrochloride is an opioid alkaloid that inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Learn More

    Starting at: $75.00

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  • BTS

    Inhibitor of ubiquitin isopeptidase activity that displays no effect on the proteolytic activity of the proteasome, and induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 values are 15.65 and 16.23 μM in E1A and E1A/C9CN cells respectively). Learn More

    Starting at: $95.00

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  • (R)-(+)-Blebbistatin

    (R)-(+)-Blebbistatin is an inactive enantiomer of the selective inhibitor of myosin II, (±)-blebbistatin. Learn More

    Starting at: $115.00

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18 Item(s)

per page