You have no items in your shopping cart.
Akt (Protein Kinase B)
-
10-DEBC hydrochloride
10-DEBC hydrochloride is a selective inhibitor of Akt/PKB, which inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Learn MoreStarting at: $90.00
-
SC 79
SC 79 is an activator of Akt which binds to the pleckstrin homology domain of Akt, and enhances Akt phosphorylation by upstream protein kinases; also enables cytosolic activation of Akt. Learn MoreStarting at: $119.00
-
API-1
API-1 is an Akt/protein kinase B (PKB) inhibitor, which binds the pleckstrin homology domain of Akt and blocks Akt membrane translocation, and inhibits EGF-induced kinase activity of Akt1, AKT2 and AKT3. Activity results in cell growth arrest and apoptosis in human cancer cells with constitutively active Akt. Learn MoreStarting at: $229.00
-
PIT 1
PIT 1, a selective PIP3 antagonist, blocks the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50 = 31.03;M) and also inhibits cancer cell survival and induces apoptosis by inhibition of PIP3-dependent PI 3-kinase/Akt signaling. Learn MoreStarting at: $119.00
-
SC 66
SC 66 is an allosteric inhibitor of Akt that interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Learn MoreStarting at: $75.00
-
FPA 124
FPA 124 is an Akt/PKB inhibitor that inhibits cell proliferation in various cancer cell lines in vitro and decreases NF-κB activity and tumor load in vivo. Learn MoreStarting at: $125.00
