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Peptide Receptors
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EMD 66684
EMD 66684 is a highly potent and very selective non-peptide angiotensin AT1 receptor antagonist (IC50 values are 0.7 and > 10000 nM for AT1 and AT2 receptors respectively), which potently inhibits angiotensin II-induced contractions in isolated rabbit aorta (IC50 = 0.2 nM) and reduces blood pressure in hypertensive rats. Learn MoreStarting at: $135.00
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NBI 27914 hydrochloride
NBI 27914 hydrochloride is a selective, non-peptide corticotropin-releasing factor1 (CRF1) receptor antagonist (Ki = 1.7 nM) which blocks behavioral seizures in vivo. Learn MoreStarting at: $110.00
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SDZ NKT 343
SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist (IC50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK2 and NK3 receptors. Learn MoreStarting at: $195.00
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CP 376395 hydrochloride
CP 376395 hydrochloride is a potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000 nM for CRF1 and CRF2 receptors respectively). Learn MoreStarting at: $135.00
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NBI 35965 hydrochloride
NBI 35965 hydrochloride is a potent and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist that inhibits cAMP accumulation and adrenocorticotropic hormone (ACTH) production in vitro and attenuates CRF and ACTH production in vivo. Learn MoreStarting at: $158.00
