Ligand-gated Ion Channels
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(RS)-4-Carboxy-3-hydroxyphenylglycine
(RS)-4-Carboxy-3-hydroxyphenylglycine is a broad spectrum EAA agonist/antagonist. Learn MoreStarting at: $135.00
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(R)-3-Carboxy-4-hydroxyphenylglycine
(R)-3-Carboxy-4-hydroxyphenylglycine is a moderately potent NMDA and AMPA/kainate receptor antagonist. Learn MoreStarting at: $280.00
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(RS)-3,4-DCPG
(RS)-3,4-DCPG is a systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG or (R)-3,4,-DCPG. Learn MoreStarting at: $105.00
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(R)-3,4-DCPG
(R)-3,4-DCPG is a AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors. Learn MoreStarting at: $140.00
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DL-AP4
DL-AP4 is a broad spectrum EAA ligand. Learn MoreStarting at: $65.00
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1-Phenylbiguanide hydrochloride
1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist. Learn MoreStarting at: $39.00
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Quipazine dimaleate
Quipazine dimaleate is a selective 5-HT3 receptor agonist with antagonist activity at peripheral 5-HT3 receptors. Learn MoreStarting at: $89.00
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SR 57227 hydrochloride
SR 57227 hydrochloride is a high affinity, selective 5-HT3 receptor agonist. Learn MoreStarting at: $99.00
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2-Methyl-5-hydroxytryptamine hydrochloride
2-Methyl-5-hydroxytryptamine hydrochloride is a 5-HT3 agonist and potent 5-HT6 ligand. Learn MoreStarting at: $75.00
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Zacopride hydrochloride
Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist and 5-HT4 receptor agonist with Ki values of 0.38nM and 373nM respectively. Learn MoreStarting at: $105.00
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MDL 72222
MDL 72222 is a 5-HT3 antagonist. Learn MoreStarting at: $95.00
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N-Methylquipazine dimaleate
N-Methylquipazine dimaleate is a 5-HT3 agonist, which has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites. Learn MoreStarting at: $105.00
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RS 16566 dihydrochloride
RS 16566 dihydrochloride is a high affinity ligand for the (R)-zacopride binding site (pKi 9.84 ). Learn MoreStarting at: $120.00
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VUF 10166
VUF 10166 is a high affinity 5-HT3 receptor antagonist (IC50 values are 0.04 and 22 nM for human 5HT3A and 5-HT3AB receptors respectively) which exhibits partial agonist activity at 5-HT3A receptors at higher concentrations (EC50 = 5.2 μM). Learn MoreStarting at: $65.00
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RS 56812 hydrochloride
RS 56812 hydrochloride is a highly potent and selective 5-HT3 partial agonist, with a pKi at 5-HT3 receptors in rat brain of 9.6, and greater than 1000-fold selectivity over a wide range of other neurotransmitter receptors. Learn MoreStarting at: $95.00
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Y-25130 hydrochloride
Y-25130 hydrochloride is a selective and potent 5-HT3 antagonist (Ki = 2.9 nM). Learn MoreStarting at: $100.00
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Ondansetron hydrochloride
Ondansetron hydrochloride is a selective 5-HT3 receptor antagonist (Ki = 6.16 nM), which is antiemetic and prevents emesis induced by cytotoxic drugs and radiation. Learn MoreStarting at: $69.00
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m-Chlorophenylbiguanide hydrochloride
m-Chlorophenylbiguanide hydrochloride is a prototypical potent and selective 5-HT3 receptor agonist. Learn MoreStarting at: $69.00
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Philanthotoxin 74
Philanthotoxin 74 is a subtype-selective AMPA receptor antagonist which inhibits homomeric GluR1, GluR3 and heteromeric GluR1/2 receptors. Learn MoreStarting at: $75.00
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(S)-CPW 399
(S)-CPW 399 is a novel subtype-selective and weakly desensitizing AMPA receptor partial agonist (Ki values are 44, 109, 223, 1890 and 2090 nM at GluR5, GluR1, GluR2, GluR3 and GluR4 receptors respectively). Learn MoreStarting at: $139.00