Ion Channels
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RuBi-Nicotine
Ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light, which exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM. Learn MoreStarting at: $299.00
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Lamotrigine isethionate
Lamotrigine isethionate is a water-soluble salt of lamotrigine, and displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Learn MoreStarting at: $90.00
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2,4-Dihydroxyphenylacetyl-L-asparagine
2,4-Dihydroxyphenylacetyl-L-asparagine is a constituent of various spider toxins. Which has been reported to be specific blocker of glutamate receptors. Learn MoreStarting at: $135.00
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bPiDDB
bPiDDB is a orthosteric neuronal nicotinic acetylcholine receptor (nAChR) antagonist. IC50 values are 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 μM at α3β4, α1β1εδ, α3β4β3, α6β4β3, α7, α4β2, α3β2β3 and α6/3β2β3 receptors respectively. Learn MoreStarting at: $89.00
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(+)-Anabasine hydrochloride
(+)-Anabasine hydrochloride is a high affinity neuronal nicotinic ACh receptor partial agonist. It stimulates Ca2+-dependent catecholamine release from rat adrenomedullary cells in vitro. Learn MoreStarting at: $72.00
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RJR 2429 dihydrochloride
RJR 2429 dihydrochloride is a potent nAChR agonist that displays selectivity for α4β2 and α1βγδ. Learn MoreStarting at: $109.00
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(±)-LY 395756
(±)-LY 395756, an analog of LY 354740, is a selective metabotropic glutamate ligand for mGlu2 and mGlu3 receptors. Learn MoreStarting at: $199.00
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TMPH hydrochloride
TMPH hydrochloride is a potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Learn MoreStarting at: $95.00
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Mecamylamine hydrochloride
Mecamylamine hydrochloride is a non-competitive nicotinic acetylcholine receptor antagonist that displays antidepressant-like effects in mice. Learn MoreStarting at: $75.00
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L-AP6
L-AP6 is a selective agonist for 'quis'-sensitized site. Learn MoreStarting at: $179.00
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4-Acetyl-1,1-dimethylpiperazinium iodide
4-Acetyl-1,1-dimethylpiperazinium iodide is a structural analog of acetylcholine that acts as a nicotinic agonist with a Ki value of 29.9 nM at α4β2. Learn MoreStarting at: $89.00
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Chlorisondamine diiodide
Chlorisondamine diiodide is an exceptionally long lasting nicotinic antagonist with IC50 value of ~1.6 mM. Learn MoreStarting at: $99.00
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(±)-Anatoxin A fumarate
(±)-Anatoxin A fumarate is a potent nicotinic agonist that stimulates [3H]-dopamine release from rat striatal synaptosomes with EC50 value of 136 nM. Learn MoreStarting at: $139.00
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1-Acetyl-4-methylpiperazine hydrochloride
1-Acetyl-4-methylpiperazine hydrochloride is a structural analog of acetylcholine that acts as a nAChR agonist. Learn MoreStarting at: $96.00
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(+)-Tubocurarine chloride
(+)-Tubocurarine chloride is a competitive, non-selective nicotinic acetylcholine receptor antagonist and also is a 5-HT3 and GABAA receptor antagonist. Learn MoreStarting at: $43.00
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Salsolinol-1-carboxylic acid
Salsolinol-1-carboxylic acid is an amino acid that occurs naturally in the CNS. Learn MoreStarting at: $95.00
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Hexamethonium bromide
Hexamethonium bromide is a Nicotinic receptor (nAChR) blocker at autonomic ganglia that induces changes in neuronal activity similar to the influences of glutamate in vitro. Learn MoreStarting at: $20.00
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Ro 0437626
Ro 0437626 is a selective P2X1 purinergic receptor antagonist (IC50 = 3 μM) that displays > 30-fold selectivity over P2X2, P2X3 and P2X2/3 receptors (IC50 > 100 μM). Learn MoreStarting at: $90.00
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MRS 2219
MRS 2219 is a selective potentiator of ATP-evoked responses at rat P2X1 receptors (EC50 = 5.9 μM). Learn MoreStarting at: $95.00
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BL 1249
BL 1249 is a putative potassium channel activator which exhibits selectivity for bladder over vascular tissue in vitro and in vivo (EC50 values are 1.26 and 21.0 μM for cultured bladder and aortic tissues respectively). Learn MoreStarting at: $115.00