Potassium Channels
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(-)-[3R,4S]-Chromanol 293B
680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) (Ki = 51 nM) which exhibits no activity against indoleamine 2,3-dioxygenase, monoamine oxidase A and B, 5-HT uptake or 5-HT1A, 1D, 2A and 2C receptors. Learn MoreStarting at: $140.00
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Chromanol 293B
(-)-[3R,4S]-Chromanol 293B is an enantiomer that selectively inhibits the slow component of delayed rectifier K+ current (IKs). Learn MoreStarting at: $135.00
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4-Aminopyridine
4-Aminopyridine is a non-selective voltage-dependent K+-channel blocker (IC50 values are 170 and 230 μM at KV1.1 and KV1.2 respectively). Learn MoreStarting at: $55.00
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ML 213
ML 213 is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively), which displays > 80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay. Learn MoreStarting at: $119.00
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L-364,373
L-364,373 is a activator of KV7.1 (KCNQ1) channels. Learn MoreStarting at: $140.00