You have no items in your shopping cart.
Glutamate (Metabotropic) Receptors
-
AMN 082 dihydrochloride
AMN 082 dihydrochloride is the first selective mGlu7 agonist, which potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Learn MoreStarting at: $89.00
-
MSOP
MSOP is a selective group III metabotropic glutamate receptor antagonist that displays an apparent KDof 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Learn MoreStarting at: $138.00
-
VU 0364770
VU 0364770 is a positive allosteric modulator at mGlu4 receptors with EC50 of 290 nM in mGlu4-expressing HEK 293 cells that prevents attentional deficit and forelimb asymmetry in a rodent model of Parkinson's disease. Learn MoreStarting at: $109.00
-
Cinnabarinic acid
Cinnabarinic acid is a mGlu4 receptor agonist that activates mGlu4 receptors in transiently transfected HEK293 cells, decreases cAMP levels in native cultured cerebellar granule cells and also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. Learn MoreStarting at: $129.00
-
MPPG
MTPG is a group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies. Learn MoreStarting at: $135.00
-
MMPIP hydrochloride
MMPIP hydrochloride is a potent allosteric mGlu7-selective receptor antagonist, which inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 values are 26 and 610 nM). Learn MoreStarting at: $65.00
-
O-Phospho-L-serine
O-Phospho-L-serine is a group III metabotropic glutamate receptor agonist; analog of L-AP4, which inhibits proliferation and enhances neuronal differentiation in progenitor cells. Learn MoreStarting at: $59.00
-
L-AP4
L-AP4 is a selective group III metabotropic glutamate receptor agonist. Synaptic depressant. Agonist at the quisqualate-sensitized AP6 site in hippocampus. Learn MoreStarting at: $60.00
