Calcium Signaling
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CGS 9343B
CGS 9343B is a Calmodulin antagonist whcih inhibits calmodulin-stimulated cAMP phosphodiesterase activity with an IC50 of 3.3 nM. Learn MoreStarting at: $135.00
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W-13 hydrochloride
W-13 hydrochloride is a calmodulin antagonist that inhibits calmodulin activated PDE activity with an IC50 of 68 μM. Learn MoreStarting at: $99.00
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A-7 hydrochloride
A-7 hydrochloride is a potent calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Learn MoreStarting at: $89.00
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W-9 hydrochloride
W-9 hydrochloride is a Calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 72 μM. Learn MoreStarting at: $109.00
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W-7 hydrochloride
W-7 hydrochloride is a calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase. Learn MoreStarting at: $99.00
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W-5 hydrochloride
W-5 hydrochloride is a Calmodulin antagonist that inhibits Ca2+-calmodulin dependent PDE with an IC50 of 240 μM. Learn MoreStarting at: $99.00
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Calmidazolium chloride
Calmidazolium chloride is a calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 μM respectively. Learn MoreStarting at: $99.00
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STO-609 acetate
STO-609 acetate is a selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase. The Ki values are 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively. Learn MoreStarting at: $69.00
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(-)-Xestospongin C
(-)-Xestospongin C is a highly potent, reversible and cell-permeable inhibitor of IP3-mediated Ca2+ release with an IC50 value of 358 nM. Learn MoreStarting at: $149.00
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Ionomycin calcium salt
Ionomycin is a calcium ionophore. Learn MoreStarting at: $99.00
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Ionomycin free acid
Ionomycin is a calcium ionophore. Learn MoreStarting at: $99.00
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NAADP tetrasodium salt
NAADP tetrasodium salt initiates Ca2+ release via type 1 ryanodine receptor (RyR1) activation and also regulates Ca2+ release from intracellular stores distinct from the endoplasmic reticulum (ER). Learn MoreStarting at: $219.00
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NPC 15199
NPC 15199 is an anti-inflammatory agent; increases intracellular Ca2+ levels. Learn MoreStarting at: $59.00
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Dantrolene, sodium salt
Dantrolene, sodium salt is an inhibits release of Ca2+ from sarcoplasmic reticulum via inhibition of ryanodine receptor (RYR) channels which displays selectivity for RYR1 and RYR3 over RYR2. Learn MoreStarting at: $55.00
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trans-Ned 19
trans-Ned 19 is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, which inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and [32P]NAADP binding (IC50 = 0.4 nM). Learn MoreStarting at: $210.00
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cis-Ned 19
cis-Ned 19 is an irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, which inhibits Ca2+ release (IC50 = 800 nM) and [32P]NAADP binding (IC50 = 15 μM). Learn MoreStarting at: $195.00
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DHBP dibromide
DHBP dibromide is a blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor. Learn MoreStarting at: $55.00
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Calpeptin
Calpeptin is a potent, cell-permeable inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Learn MoreStarting at: $90.00
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MDL 28170
MDL 28170 is a potent, selective inhibitor of calpain and cathepsin B that rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Learn MoreStarting at: $65.00