5-HT7 Receptors
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AS 19
AS 19 is a potent 5-HT7 receptor agonist (IC50 = 0.83 nM), that enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo. Learn MoreStarting at: $109.00
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LP 12 hydrochloride
LP 12 hydrochloride is a 5-HT7 receptor agonist displaying selectivity over D2, 5-HT1A and 5-HT2A receptors (Ki values are 0.22, 7.3, 52.7 and 326 nM respectively), which induces relaxation of substance P-induced contractions in guinea pig ileum (EC50 = 1.77 μM). Learn MoreStarting at: $135.00
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LP 20 hydrochloride
LP 20 hydrochloride is a ligand of the 5-HT7 receptor (Ki = 2.6 nM) which exhibits agonist and antagonist activity. It also displays selectivity over adrenergic α1 and 5-HT1A receptors (Ki values are 156 and 476 nM respectively). Learn MoreStarting at: $115.00
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SB 258719 hydrochloride
SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist that displays > 100-fold selectivity over a range of other receptors. Learn MoreStarting at: $119.00
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SB 269970 hydrochloride
SB 269970 hydrochloride is a potent and selective 5-HT7 receptor antagonist (pKi values are 8.9, 7.2 and 6.0 for 5-HT7A, 5-HT5A and 5-HT1B and < 6.0 for 5-HT1A, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT4 and 5-HT6 receptors respectively). Learn MoreStarting at: $135.00
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LP 44
LP 44 is a high affinity 5-HT7 receptor agonist that displays selectivity over 5-HT1A and 5-HT2A receptors (200- and > 1000-fold respectively). Learn MoreStarting at: $145.00