Cannabinoid Receptors
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Tocrifluor T1117
Tocrifluor T1117 is a novel fluorescent form of AM 251, which conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543nm excitation (590nm emission), and displays GPR55 binding activity. Learn MoreStarting at: $200.00
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GGTI 297
GGTI 297 is a geranylgeranyltransferase I (GGTase-I) inhibitor (IC50 values are 135 and 418 nM for GGTase-I and FTase inhibition respectively), which inhibits RhoA prenylation leading to inactivation of RhoA/ROCK and a decrease in basal tone of the internal anal sphincter in vitro. Learn MoreStarting at: $149.00
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MJ 15
MJ 15 is a potent and selective CB1 receptor antagonist that inhibits food intake and increases in body weight in diet-induced obese rats and mice. Learn MoreStarting at: $139.00
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PF 514273
PF 514273 is a potent and selective CB1 receptor antagonist that inhibits food intake in vivo following oral administration. Learn MoreStarting at: $139.00
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(±)-CP 47497
(±)-CP 47497 is a potent CB1 receptor agonist (Ki = 2.2 nM)that exhibits analgesic, motor depressant, anticonvulsant and hypothermic effects in vivo. Learn MoreStarting at: $99.00
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TC-C 14G
TC-C 14G is a potent, high affinity CB1 receptor inverse agonist with high efficacy in a hypothermia assay (ID50 = 5 mg/kg) in vivo. Learn MoreStarting at: $140.00
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NIDA 41020
NIDA 41020 is a high affinity CB1 receptor antagonist (Ki = 4.1 nM), which exhibits significantly reduced lipophilicity compared to other CB1 antagonists. Learn MoreStarting at: $139.00
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Oleamide
Oleamide endogenous sleep-inducing lipid, which acts as an agonist at the CB1 cannabinoid receptor (EC50 = 1.64 μM). Learn MoreStarting at: $59.00
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ACPA
ACPA is a potent and selective CB1 agonist (Ki = 2.2 nM) which displays 325-fold selectivity over CB2 receptors. Learn MoreStarting at: $69.00
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Noladin ether
Noladin ether is an endogenous agonist for the GPR55 and CB1 receptors (EC50 values are 10 and 37 nM respectively) that displays selectivity over CB2 receptors (Ki values are 21.2 nM and > 3mM at CB1 and CB2 respectively). Learn MoreStarting at: $98.00
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ACEA
ACEA is a potent and highly selective CB1 receptor agonist (Ki = 1.4 nM) which displays >1400-fold selectivity over CB2 receptors. Learn MoreStarting at: $55.00
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Arvanil
Arvanil is a cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist (Ki values are 0.5 and 0.3 μM respectively), which also inhibits the anandamide transporter (IC50 = 3.6 μM). Learn MoreStarting at: $50.00
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Leelamine hydrochloride
Leelamine hydrochloride is a CB1 agonist which displaces binding of [3H]-SR141716A with an IC50 value of 2.86 μM. Learn MoreStarting at: $90.00
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DEA
DEA is a potent endocannabinoid and anandamide analog that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (Ki = 34.4 nM). Learn MoreStarting at: $80.00
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(R)-(+)-Methanandamide
(R)-(+)-Methanandamide is a stable anandamide analog that is a selective agonist for the CB1 receptor (Ki values are 20 and 815 nM for CB1 and CB2 receptors respectively), which also displays agonist activity at vanilloid receptors. Learn MoreStarting at: $65.00
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LY 320135
LY 320135 is a potent CB1 receptor antagonist/inverse agonist (Ki = 141 nM) with greater than 70-fold selectivity over CB2 receptors (Ki > 10 μM). Learn MoreStarting at: $135.00
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NADA
NADA is a potent endogenous cannabinoid and vanilloid receptor agonist, with no action at dopamine receptors. Selective for CB1 over CB2 receptors (Ki values are 0.25 and 12 μM respectively), and potent agonist at TRPV1 (VR1) receptors (EC50 ~ 50 nM). Learn MoreStarting at: $79.00
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AM 281
AM 281 is a potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively), which increases locomotor activity following systemic administration in vivo. Learn MoreStarting at: $140.00
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GP 2a
GP 2a is a selective CB2 receptor agonist with Ki values of 7.6 and 900 nM for CB2 and CB1 receptors respectively. Learn MoreStarting at: $169.00
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CB 65
CB 65 is a high affinity and selective CB2 receptor agonist. Learn MoreStarting at: $139.00