Wnt Signaling
-
exo-IWR 1
exo-IWR 1 is negative control for endo-IWR 1. It also exhibits decreased activity against the Wnt/β-catenin pathway. Learn MoreStarting at: $90.00
-
PNU 74654
PNU 74654 Binds to β-catenin (KD = 450 nM) and inhibits the interaction between β-catenin and T cell factor 4 (Tcf4) and disrupts the Wnt signaling pathway. Learn MoreStarting at: $90.00
-
CCT 031374 hydrobromide
CCT 031374 hydrobromide is an inhibitor of TCF-dependent transcription, which blocks BIO-induced β-catenin stabilization; reduces nuclear and cytosolic β-catenin levels in mouse L-cells, and inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells. Learn MoreStarting at: $105.00
-
Cardionogen 1
Cardionogen 1, a wnt signaling modulator, potently inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos and Enlarges heart size via cardiomyocyte hyperplasia; induces ES cell cardiac differentiation. Learn MoreStarting at: $139.00
-
iCRT 14
iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) with IC50 of 40.3 nM in assays of Wnt pathway activity. Learn MoreStarting at: $139.00
-
ICG 001
ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription that inhibits β-catenin/CBP interaction. Learn MoreStarting at: $99.00
-
JW 67
JW 67 is an inhibitor of canonical Wnt pathway signaling (IC50 = 1.17 μM); targets the β-catenin destruction complex (GSK-3β/AXIN/APC) to induce β-catenin degradation. Learn MoreStarting at: $109.00