Synthases/Synthetases
-
EIT hydrobromide
EIT hydrobromide is a potent, selective and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Learn MoreStarting at: $50.00
-
(S)-Methylisothiourea sulfate
(S)-Methylisothiourea sulfate is a highly selective, potent competitive inhibitor of iNOS. Learn MoreStarting at: $79.00
-
BYK 191023 dihydrochloride
BYK 191023 dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS) that acts in an NADPH- and time-dependent manner. Learn MoreStarting at: $119.00
-
S-Isopropylisothiourea hydrobromide
S-Isopropylisothiourea hydrobromide is a potent inhibitor of NO synthase, with selectivity for the inducible form. Learn MoreStarting at: $69.00
-
2-Iminopiperidine hydrochloride
SR 11302 is an inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumor effects in vivo. Learn MoreStarting at: $70.00
-
AR-C 102222
AR-C 102222 is an inducible nitric oxide synthase (iNOS) inhibitor; selective for iNOS over eNOS (IC50 values are 0.037 and >100 μM for iNOS and eNOS respectively) and exhibits antinociceptive and anti-inflammatory activity in rodent pain models. Learn MoreStarting at: $159.00
-
AMT hydrochloride
AMT hydrochloride is a potent, selective and reversible inhibitor of iNOS (IC50 = 3.6 nM). Learn MoreStarting at: $85.00
-
Aminoguanidine hydrochloride
Aminoguanidine hydrochloride is an irreversible inhibitor of iNOS that displays some selectivity over eNOS and nNOS. Learn MoreStarting at: $65.00
-
1400W dihydrochloride
1400W dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM) which is selective over nNOS and eNOS (Ki values are 2 and 50 μM respectively). Learn MoreStarting at: $100.00
-
L-NIL hydrochloride
L-NIL hydrochloride is a selective inhibitor of inducible nitric oxide synthase (IC50 = 3.3 μM). Learn MoreStarting at: $90.00
-
C 75
C 75 is a synthetic inhibitor of fatty acid synthase (FAS) which inhibits fatty acid synthesis in vitro and in vivo and displays anorectic effects. Induces apoptosis in MCF-7 xenografts and exhibits anti-tumor activity. Learn MoreStarting at: $135.00
-
N1,N12-Diethylspermine tetrahydrochloride
N1,N12-Diethylspermine tetrahydrochloride is a powerful antineoplastic agent in cultured cells and animal tumors (IC50 = 0.2 μM in L1210 cells). Learn MoreStarting at: $90.00
-
Nω-Propyl-L-arginine hydrochloride
Nω-Propyl-L-arginine hydrochloride is a highly selective and potent inhibitor of nNOS (Ki = 57 nM) which displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Learn MoreStarting at: $120.00
-
ARL 17477 dihydrochloride
ARL 17477 dihydrochloride is a selective neuronal nitrogen oxide synthase (nNOS) inhibitor (IC50 values are 1 and 17 μM for nNOS and endothelial NOS respectively). Learn MoreStarting at: $95.00
-
3-Bromo-7-nitroindazole
3-Bromo-7-nitroindazole is a potent inhibitor of rat cerebellar nitric oxide synthase that is more potent than 7-nitroindazole. Learn MoreStarting at: $89.00
-
L-NMMA acetate
L-NMMA acetate is competitive, irreversible inhibitor of all three NOS isoforms. Learn MoreStarting at: $49.00
-
L-NAME hydrochloride
L-NAME hydrochloride is a NO synthase inhibitor. Learn MoreStarting at: $49.00
-
7-Nitroindazole
7-Nitroindazole is a reversible, competitive and non-selective NOS inhibitor. Learn MoreStarting at: $65.00
-
7-NINA
7-NINA is a sodium salt of the non-selective NOS inhibitor 7-nitroindazole. Learn MoreStarting at: $69.00
-
TRIM
TRIM is a potent inhibitor of neuronal and inducible NO synthases, with much lower affinity for the endothelial isoform (displays IC50 values of 28.2, 27.0 and 1057.5 μM respectively). Learn MoreStarting at: $59.00