G Proteins
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CCG 2046
CCG 2046 is an inhibitor of regulator of G-protein signaling 4 (RGS4), which reduces the RGS4-Gαo protein-protein interaction signal. Learn MoreStarting at: $90.00
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Gallein
Gallein is an inhibitor of G protein βγ subunit-dependent signaling, which blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells. Learn MoreStarting at: $55.00
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Gue 1654
Gue 1654 is an oxoeicosanoid receptor 1 (OXE-R) modulator, which selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R. Learn MoreStarting at: $90.00
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8-Bromo-cGMP, sodium salt
Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. Learn MoreStarting at: $55.00
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SCH 202676 hydrobromide
SCH 202676 hydrobromide is a sulphydryl-reactive compound that inhibits agonist and antagonist binding to G-protein-coupled receptors that inhibits a variety of GPCRs including adenosine, opioid, muscarinic, adrenergic and dopaminergic receptors IC50 values of 0.1-1.8 μM. Learn MoreStarting at: $115.00
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SecinH3
SecinH3 is a sec7-specific GEF inhibitor that inhibits insulin signaling via inhibition of insulin receptor substrate protein (IRS) phosphorylation. Learn MoreStarting at: $169.00
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CCG 50014
CCG 50014 is a potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein that exhibits >20-fold selectivity for RGS4 over other RGS proteins. Learn MoreStarting at: $125.00