Retinoid X Receptors
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Fluorobexarotene
Fluorobexarotene is a RXR agonist (Ki = 12 nM; EC50 = 43 nM at RXRα receptors), which displays similar RAR agonist activity to bexarotene; exhibits an apparent RXR binding affinity 75% greater than bexarotene. Learn MoreStarting at: $160.00
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SR 11237
SR 11237 is a pan retinoid X receptor (RXR) agonist that is devoid of any RAR activity. Learn MoreStarting at: $135.00
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LG 100754
LG 100754 is a novel RXR:PPARγ agonist; sensitizes PPARγ by enhancing its ligand binding activity which displays selectivity over other permissive heterodimers such as RXR:LXRα and RXR:BAR/FXR. Learn MoreStarting at: $140.00
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HX 531
HX 531 is a potent RXR antagonist (IC50 = 18 nM). Learn MoreStarting at: $149.00
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HX 630
HX 630 is a RXR agonist, which acts as a retinoid synergist and enhances the potency of AM 80 in a HL-60 cell differentiation assay. Learn MoreStarting at: $149.00
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CD 3254
CD 3254 is a selective RXRα agonist; exhibits no activity at RARα, RARβ or RARγ receptors. Learn MoreStarting at: $135.00
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LG 101506
LG 101506 is a selective RXR modulator (Ki values are 3, 9 and 11 for RXRα, RXRβ and RXRγ respectively), which displays poor binding affinity for RAR isoforms (Ki values are 2746, 3516 and >10,000 nM for RARα, RARβ and RARγ respectively). Learn MoreStarting at: $139.00
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Docosahexaenoic acid
Docosahexaenoic acid is a endogenous omega-3 fatty acid. It acts as a selective retinoid X receptor (RXR) agonist that displays no activity at RAR, thyroid hormone receptor or the vitamin D receptor (VDR). Learn MoreStarting at: $75.00
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UVI 3003
UVI 3003 is a RXR antagonist that displays high RXR binding affinity. Learn MoreStarting at: $115.00