Leukotriene and Related Receptors
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SR 2640 hydrochloride
SR 2640 hydrochloride is a potent and selective competitive leukotriene D4 and E4 receptor antagonist,which Inhibits LTD4-, trachea contraction (pA2 = 8.7) and LTD4-attenuation of human PMN chemotaxis. Learn MoreStarting at: $95.00
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5-Oxo-ETE
5-Oxo-ETE is a potent oxoeicosanoid (OXE) receptor agonist (EC50 = 0.33 nM). Learn MoreStarting at: $179.00
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MK 571
MK 571 is a potent CysLT1 (LTD4) leukotriene receptor inverse agonist (EC50 = 1.3 nM), which antagonizes LTD4-induced contractions of guinea pig trachea and ileum (pA2 values are 9.4 and 10.5 respectively). Learn MoreStarting at: $110.00
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Cinalukast
Cinalukast is a potent, selective CysLT1 (LTD4) leukotriene receptor antagonist (IC50 = 6.4 nM), which inhibits LTD4-induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol. Learn MoreStarting at: $105.00
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BAY-u 9773
BAY-u 9773 is a cysteinyl leukotriene receptor antagonist with equal affinity at both CysLT1 and CysLT2 receptors (pKB values are 6.8 and 6.5 respectively). Learn MoreStarting at: $95.00
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FPL 55712
FPL 55712 is a leukotriene receptor antagonist which inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4. Learn MoreStarting at: $149.00
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Leukotriene B4
Leukotriene B4 is a potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. It binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Learn MoreStarting at: $269.00
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LY 171883
LY 171883 is a selective, orally active leukotriene D4 (LTD4) antagonist and also acts as an agonist at peroxisome proliferator-activated receptors (PPARs). Learn MoreStarting at: $75.00