γ-Secretase
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Compound W
Compound W is an inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). Learn MoreStarting at: $55.00
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L-685,458
L-685,458 is a potent and selective γ-secretase inhibitor (IC50 = 17 nM) that displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Learn MoreStarting at: $189.00
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JLK 6
JLK 6 is inhibitor of γ-secretase that selectively inhibits βAPP cleavage without affecting other γ-secretase-mediated pathways. Learn MoreStarting at: $109.00
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MRK 560
MRK 560 inhibits proteolytic cleavage of amyloid precursor protein (APP) over the Notch pathway. Learn MoreStarting at: $149.00