DNA, RNA and Protein Synthesis
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Trovafloxacin mesylate
Fluoroquinolone antibiotic. Inhibits bacterial DNA topoisomerase IV and DNA gyrase and forms a stable quinolone-DNA complex with these enzymes which reversibly inhibits DNA synthesis. Displays potent activity against gram-positive and gram-negative bacteria. Increases the production of mitochondrial NO in immortalized hepatocytes; also increases mitochondrial Ca2+. Learn MoreStarting at: $135.00
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Homoharringtonine
Homoharringtonine is an inhibitor of protein synthesis which blocks elongation phase of translation by binding to the 60-S ribosome subunit. Learn MoreStarting at: $119.00
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Viomycin
Viomycin is a member of the tuberactinomycin family of antibiotics, which inhibits group I intron splicing and prokaryotic protein synthesis. Learn MoreStarting at: $109.00
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8-Chloroadenosine
8-Chloroadenosine is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP, which incorporates into RNA during transcription and inhibits RNA synthesis and exhibits cytotoxicity in MM.1S, RPMI-8226 and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic catastrophe in A549 and H1299 cells. Learn MoreStarting at: $145.00