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Search results for 'U 0126'
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Galanthamine hydrobromide
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Learn MoreStarting at: $75.00
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2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine is a GTP cyclohydrolase I (GCH1) inhibitor, which exhibits more potent inhibition of GCH1 in the presence of GFRP (GTP cyclohydrolase feedback-regulatory protein). Learn MoreStarting at: $69.00
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GABA
GABA is an endogenous inhibitory neurotransmitter. Learn MoreStarting at: $45.00
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Caffeine
Caffeine is a central nervous system stimulant, which mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors. Learn MoreStarting at: $69.00
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DIM
DIM is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines, which inhibits phosphorylation of EGFR and downstream activation of ERK. Learn MoreStarting at: $39.00
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Thiolutin
Thiolutin is Antibiotic, inhibits bacterial RNA polymerase, Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and suppresses tumor cell-induced angiogenesis. Learn MoreStarting at: $99.00
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3,5-DHBA
3,5-DHBA is a selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM), Inhibits lipolysis in wild-type mouse adipocytes. Learn MoreStarting at: $59.00
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m-Chlorophenylbiguanide hydrochloride
m-Chlorophenylbiguanide hydrochloride is a prototypical potent and selective 5-HT3 receptor agonist. Learn MoreStarting at: $69.00
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Cucurbitacin I
Cucurbitacin I is a selective inhibitor of STAT3/JAK2 signaling, which inhibits the activation of STAT3 and JAK2 and displays no activity on Src, Akt, ERK and JNK. Learn MoreStarting at: $169.00
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Kynurenic acid sodium salt
Kynurenic acid sodium salt is a sodium salt of kynurenic acid, and it is a broad spectrum EAA antagonist. Learn MoreStarting at: $79.00
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Chicago Sky Blue 6B
Chicago Sky Blue 6B is a potent inhibitor of L-glutamate uptake into synaptic vesicles, which inhibits macrophage migration inhibitory factor (MIF) (IC50 = 0.81 μM) and MIF proinflammatory activity. Learn MoreStarting at: $49.00
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S-Trityl-L-cysteine
S-Trityl-L-cysteine is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50 = 1 mM) and microtubule-activated ATPase activity of Eg5 (IC50 = 140 nM). Learn MoreStarting at: $65.00
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DL-Dithiothreitol
DL-Dithiothreitol is a reagent for maintaining SH groups in the reduced state. Learn MoreStarting at: $119.00
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Valerenic acid
Valerenic acid is a positive allosteric modulator of GABAA receptors, which wdisplays preference for receptors containing β2 or β3 subunits and activates the receptor and also blocks the channel at high concentrations. Learn MoreStarting at: $85.00
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ZM 449829
Potent is a selective inhibitor of Janus tyrosine kinase 3 (JAK3), which binds competitively to the JAK3 ATP site. And inhibits STAT-5 phosphorylation and T-cell proliferation. Learn MoreStarting at: $89.00
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Mexiletine hydrochloride
Mexiletine hydrochloride is an use-dependent sodium channel blocker (IC50 values are 75.3 and 23.6 μM for tonic and use-dependent block respectively). Learn MoreStarting at: $49.00
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SU 4312
SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). Learn MoreStarting at: $189.00
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Sodium citrate
Sodium citrate is commonly used laboratory reagent Learn MoreStarting at: $39.00
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DHBP dibromide
DHBP dibromide is a blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor. Learn MoreStarting at: $55.00
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Pentoxifylline
Pentoxifylline is a phosphodiesterase inhibitor that blocks production of TNF-&alpha and other cytokines. Learn MoreStarting at: $69.00
