You have no items in your shopping cart.
Search results for 'LY 215840'
-
Pronethalol hydrochloride
Pronethalol hydrochloride is a ??-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias. Learn MoreStarting at: $69.00
-
Galanthamine hydrobromide
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Learn MoreStarting at: $75.00
-
DIM
DIM is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines, which inhibits phosphorylation of EGFR and downstream activation of ERK. Learn MoreStarting at: $39.00
-
Rottlerin
Rottlerin is riginally reported to inhibit PKC isoforms, inhibit CAM kinase III, and inhibit a wide range of protein kinases. Learn MoreStarting at: $69.00
-
Thiolutin
Thiolutin is Antibiotic, inhibits bacterial RNA polymerase, Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and suppresses tumor cell-induced angiogenesis. Learn MoreStarting at: $99.00
-
3,5-DHBA
3,5-DHBA is a selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM), Inhibits lipolysis in wild-type mouse adipocytes. Learn MoreStarting at: $59.00
-
ZM 449829
Potent is a selective inhibitor of Janus tyrosine kinase 3 (JAK3), which binds competitively to the JAK3 ATP site. And inhibits STAT-5 phosphorylation and T-cell proliferation. Learn MoreStarting at: $89.00
-
Mexiletine hydrochloride
Mexiletine hydrochloride is an use-dependent sodium channel blocker (IC50 values are 75.3 and 23.6 μM for tonic and use-dependent block respectively). Learn MoreStarting at: $49.00
-
SU 4312
SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). Learn MoreStarting at: $189.00
-
Sodium citrate
Sodium citrate is commonly used laboratory reagent Learn MoreStarting at: $39.00
-
Calcium chloride dihydrate
Calcium chloride dihydrate is a commonly used laboratory reagent Learn MoreStarting at: $79.00
-
CY 208-243
CY 208-243 is a centrally active dopamine D1 receptor agonist, selective over D2 receptor sites, which stimulates adenylate cyclase in rat striatal homogenates with an EC50 of 125 nM, that exerts antiParkinsonian activity in animal models. Learn MoreStarting at: $139.00
-
PF 04691502
PF 04691502 is an potent and selective dual ATP-competitive PI 3-K/mTOR inhibitor (Ki values are 1.6, 1.8, 1.9, 2.1 and 16 nM for human PI 3-K δ, α, γ, β, and mTOR, respectively). Learn MoreStarting at: $145.00
-
Olomoucine
Olomoucine is a cyclin-dependent kinase inhibitor that competes for the ATP binding site of the kinase and selectively inhibits cdc2/cyclin B (IC50 = 7 μM), cdk2/cyclin A (IC50 = 7 μM), cdk2/cyclin E (IC50 = 7 μM), cdk/p35 kinase (IC50 = 3 μM) and ERK1/MAP kinase (IC50 = 25 μM). Arrests human fibroblasts in the G1 phase. Learn MoreStarting at: $99.00
-
AF-DX 116
AF-DX 116 is a selective M2 muscarinic receptor antagonist. Ki values are 64, 417, 786, 211 and 5130 nM for human recombinant M2, M1, M3, M4 and M5 muscarinic receptors, respectively. Learn MoreStarting at: $105.00
-
Jasplakinolide
Jasplakinolide Rapidly stabilizes pre-formed actin filaments and inhibits their disassembly in vitro.It also induces polymerization of actin monomers into F-actin in vivo. Learn MoreStarting at: $205.00
-
RN 1747
RN 1747 is a selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively) which displays selectivity over other TRP channels (EC50 values are 0.77, >30, >30 and >100 μM for TRPV4, TRPM8, TRPV3 and TRPV1 receptors respectively). Learn MoreStarting at: $95.00
-
RX 821002 hydrochloride
RX 821002 hydrochloride is a potent, selective α2-adrenoceptor antagonist with very low affinity for imidazoline sites which displays selectivity for the α2D over the α2A subtypes (pKd values are 9.7 and 8.2 respectively). Learn MoreStarting at: $49.00
-
RO-3
RO-3 is a selective homomeric P2X3 and heteromeric P2X2/3 receptor antagonist (pIC50 values are 7.0 and 5.9 respectively) that exhibits no activity at P2X1, P2X2, P2X4, P2X5 and P2X7 receptors (IC50 > 10 μM). Learn MoreStarting at: $105.00
-
VUF 10460
VUF 10460 is a selective histamine H4 receptor agonist which displays 50-fold selectivity for the rat H4 receptor over the H3 subtype (pKi values are 5.75 and 7.46 for rat H3 and H4 receptors respectively). Also exhibits affinity for the human H4 receptor (pKi = 8.22). Learn MoreStarting at: $129.00
