Search results for 'Anandamide'
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Oleylethanolamide
Oleylethanolamide is a lipid mediator and analog of anandamide that is involved in peripheral regulation of feeding, which induces satiety through activation of PPARα and is also a ceramidase inhibitor. Learn MoreStarting at: $60.00
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Arvanil
Arvanil is a cannabinoid CB1 and vanilloid TRPV1 (VR1) agonist (Ki values are 0.5 and 0.3 μM respectively), which also inhibits the anandamide transporter (IC50 = 3.6 μM). Learn MoreStarting at: $50.00
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PALDA
PALDA is an endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Learn MoreStarting at: $75.00
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AACOCF3
AACOCF3 is an inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Learn MoreStarting at: $65.00
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DEA
DEA is a potent endocannabinoid and anandamide analog that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (Ki = 34.4 nM). Learn MoreStarting at: $80.00
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(R)-(+)-Methanandamide
(R)-(+)-Methanandamide is a stable anandamide analog that is a selective agonist for the CB1 receptor (Ki values are 20 and 815 nM for CB1 and CB2 receptors respectively), which also displays agonist activity at vanilloid receptors. Learn MoreStarting at: $65.00
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N-Arachidonylglycine
N-Arachidonylglycine is an endogenous anandamide-like compound. Learn MoreStarting at: $85.00
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MAFP
MAFP is a potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC50 = 2.5 nM). It also binds irreversibly to CB1 receptors (IC50 = 20 nM). Learn MoreStarting at: $98.00
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Palmitoylisopropylamide
Palmitoylisopropylamide is an inhibitor of fatty acid amide hydrolase (FAAH); pIC50 = 4.89 for inhibition of [3H]-anandamide metabolism. Learn MoreStarting at: $65.00
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AM 404
AM 404 is a competitive and selective inhibitor of carrier-mediated anandamide transport (IC50 = 1 μM). Does not activate CB1 receptors or inhibit anandamide hydrolysis but has been shown to activate native and cloned vanilloid receptors (pEC50 = 7.4). Active in vivo. Also available in water soluble emulsion . Learn MoreStarting at: $65.00
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AM 1172
AM 1172 metabolically stable anandamide uptake inhibitor (IC50 = 2.1 - 2.5 μM) and fatty acid amide hydrolase (FAAH) inhibitor (Ki = 3.18 μM). Learn MoreStarting at: $139.00
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Virodhamine
Virodhamine endogenous cannabinoid receptor mixed agonist/antagonist found in higher concentrations peripherally than anandamide. Learn MoreStarting at: $79.00
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VDM 11
VDM 11 is a potent and selective inhibitor of the anandamide membrane transporter (AMT) with IC50 values of 4-11 μM, which displays negligible agonist activity at the hVR1 receptor and very weak action at CB1 and CB2 receptors. Learn MoreStarting at: $75.00
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UCM 707
UCM 707 is a potent endocannabinoid transport inhibitor. IC50 values are 0.8 and 30 μM for inhibition of the anandamide transporter and FAAH respectively. Ki values are 4700, 67 and > 5000 nM for CB1, CB2 and VR1 receptors respectively. Learn MoreStarting at: $125.00
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O-2093
O-2093 is an inhibitor of anandamide uptake (IC50 = 17.3 μM) with little or no activity at CB1, CB2, TRPV1 and FAAH. Learn MoreStarting at: $99.00
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O-1918
O-1918 is a selective, silent antagonist of a putative endothelial anandamide receptor distinct from CB1 or CB2 receptors. Learn MoreStarting at: $149.00
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Olvanil
Olvanil, a potent vanilloid receptor agonist, blocks anandamide uptake (IC50 = 9 μM) and may bind to CB1 cannabinoid receptors. Learn MoreStarting at: $99.00
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OMDM-2
OMDM-2 is a metabolically stable inhibitor of anandamide cellular uptake that displays relatively low affinity for CB1 and CB2 receptors with Ki values of 5.1 and > 10 μM and for vanilloid VR1 receptors with EC50 value of 10 μM. Learn MoreStarting at: $65.00
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Anandamide
Anandamide is an endogenous cannabinoid and TRPV1 receptor agonist that also blocks TNF-α-induced NF-κB activation via direct inhibition of IKK. Learn MoreStarting at: $59.00
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Anandamide - d4
Anandamide - d4 is a deuterated anandamide that is used as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. Learn MoreStarting at: $149.00