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Search results for '10'
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Pronethalol hydrochloride
Pronethalol hydrochloride is a ??-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias. Learn MoreStarting at: $69.00
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Spironolactone
Spironolactone is a competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo, displays antiandrogen activity and inhibits steroid hormone biosynthesis. Learn MoreStarting at: $45.00
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Galanthamine hydrobromide
Galanthamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Learn MoreStarting at: $75.00
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2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine is a GTP cyclohydrolase I (GCH1) inhibitor, which exhibits more potent inhibition of GCH1 in the presence of GFRP (GTP cyclohydrolase feedback-regulatory protein). Learn MoreStarting at: $69.00
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GABA
GABA is an endogenous inhibitory neurotransmitter. Learn MoreStarting at: $45.00
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Caffeine
Caffeine is a central nervous system stimulant, which mobilizes calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors. Learn MoreStarting at: $69.00
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DIM
DIM is an activator of Chk2 that causes G2/M cell cycle arrest in various cancer cell lines, which inhibits phosphorylation of EGFR and downstream activation of ERK. Learn MoreStarting at: $39.00
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Rottlerin
Rottlerin is riginally reported to inhibit PKC isoforms, inhibit CAM kinase III, and inhibit a wide range of protein kinases. Learn MoreStarting at: $69.00
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Prochlorperazine dimaleate
Prochlorperazine dimaleate is a D2 receptor antagonist. Learn MoreStarting at: $55.00
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Thiolutin
Thiolutin is Antibiotic, inhibits bacterial RNA polymerase, Inhibits adhesion of HUVEC cells to vitronectin (IC50 = 0.83 mM) and suppresses tumor cell-induced angiogenesis. Learn MoreStarting at: $99.00
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3,5-DHBA
3,5-DHBA is a selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM), Inhibits lipolysis in wild-type mouse adipocytes. Learn MoreStarting at: $59.00
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m-Chlorophenylbiguanide hydrochloride
m-Chlorophenylbiguanide hydrochloride is a prototypical potent and selective 5-HT3 receptor agonist. Learn MoreStarting at: $69.00
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Cucurbitacin I
Cucurbitacin I is a selective inhibitor of STAT3/JAK2 signaling, which inhibits the activation of STAT3 and JAK2 and displays no activity on Src, Akt, ERK and JNK. Learn MoreStarting at: $169.00
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Kynurenic acid sodium salt
Kynurenic acid sodium salt is a sodium salt of kynurenic acid, and it is a broad spectrum EAA antagonist. Learn MoreStarting at: $79.00
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(±)-Acetylcarnitine chloride
(±)-Acetylcarnitine chloride is weak cholinergic agonist and important intermediates in lipid metabolism. Learn MoreStarting at: $49.00
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Chicago Sky Blue 6B
Chicago Sky Blue 6B is a potent inhibitor of L-glutamate uptake into synaptic vesicles, which inhibits macrophage migration inhibitory factor (MIF) (IC50 = 0.81 μM) and MIF proinflammatory activity. Learn MoreStarting at: $49.00
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S-Trityl-L-cysteine
S-Trityl-L-cysteine is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50 = 1 mM) and microtubule-activated ATPase activity of Eg5 (IC50 = 140 nM). Learn MoreStarting at: $65.00
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DL-Dithiothreitol
DL-Dithiothreitol is a reagent for maintaining SH groups in the reduced state. Learn MoreStarting at: $119.00
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Valerenic acid
Valerenic acid is a positive allosteric modulator of GABAA receptors, which wdisplays preference for receptors containing β2 or β3 subunits and activates the receptor and also blocks the channel at high concentrations. Learn MoreStarting at: $85.00
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ZM 449829
Potent is a selective inhibitor of Janus tyrosine kinase 3 (JAK3), which binds competitively to the JAK3 ATP site. And inhibits STAT-5 phosphorylation and T-cell proliferation. Learn MoreStarting at: $89.00
