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RuBi-Glutamate

RuBi-Glutamate is a Ruthenium-bipyridine-triphenylphosphine caged glutamate that can be excited by visible wavelengths and releases glutamate after one- or two-photon excitation. Learn More

Starting at: $149.00

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HDS 029

HDS 029 is a potent inhibitor of the ErbB receptor family that inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells. Learn More

Starting at: $85.00

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Chetomin

Chetomin targets the CH1 domain of CBP/p300; inhibits interaction of HIF-1α, HIF-2α and STAT2 with CBP/p300. Attenuates hypoxia-induced gene expression in vitro and in vivo; radiosensitizes human HT 1080 fibrosarcoma cells in vitro. Learn More

Starting at: $125.00

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ML 228

ML 228 is a HIF pathway activator (EC50 values are 1.23 and 1.4 μM for HRE gene reporter assay and HIF-1α nuclear translocation assay respectively); acts via chelation of iron, independently of PHD. Also exhibits > 80% inhibition of the human A3 receptor, dopamine transporter, μ receptor, hERG and 5-HT2B receptor, and rat sodium channel site 2, at a concentration of 10 μM. Learn More

Starting at: $135.00

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Tyrphostin B44, (-) enantiomer

Tyrphostin B44, (-) enantiomer is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), which is more active than the (+) enantiomer. Selective over ErbB2. Learn More

Starting at: $75.00

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