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Search results for 'PI'
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BIBU 1361 dihydrochloride
BIBU 1361 dihydrochloride is a potent inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase that inhibits growth of established human xenografts in athymic mice. Learn MoreStarting at: $85.00
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PD 158780
PD 158780 is a potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively), which induces G1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells. Learn MoreStarting at: $135.00
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AG 556
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 μM) and selective over ErbB2 (IC50 > 500 μM). Learn MoreStarting at: $80.00
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Tyrphostin B44, (+) enantiomer
Tyrphostin B44, (+) enantiomer is an epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.86 μM). Learn MoreStarting at: $105.00
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AG 494
AG 494 is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Learn MoreStarting at: $85.00
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AG 555
AG 555 is a potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 μM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Learn MoreStarting at: $80.00
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Tyrphostin B44, (-) enantiomer
Tyrphostin B44, (-) enantiomer is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), which is more active than the (+) enantiomer. Selective over ErbB2. Learn MoreStarting at: $75.00
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Lavendustin A
Lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 11 nM), which inhibits p60c-src with an IC50 of 500 nM and is selective over PKA, PKC and PI 3-kinase (IC50 > 100 μM). Learn MoreStarting at: $115.00
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AG 99
AG 99 is an epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM) that is selective over insulin receptor kinase. Learn MoreStarting at: $85.00
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AG 18
AG 18 is an inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 μM respectively, whichi inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling. Learn MoreStarting at: $80.00
