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Search results for 'ganoderic acid'
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Anti-PIKFyve
Anti-PIKFyve is an antibody raised against recombinant protein corresponding to amino acid residues 1083-1200 of human PIKfyve . Learn MoreStarting at: $299.00
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LUF 6283
LUF 6283 is a partial agonist of hydroxycarboxylic acid receptor 2 (HCA2) with a Ki value of 0.55 μM. Learn MoreStarting at: $89.00
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MEDICA 16
MEDICA 16 is a free fatty acid 1 (FFA1/GPR40) receptor agonist that reduces intracellular triacylglycerol levels in muscle and inhibits lipogenesis and increases insulin sensitivity in rodents in vivo. Learn MoreStarting at: $115.00
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Grifolic acid
Grifolic acid is a selective partial GPR120 agonist that induces ERK and [Ca2+]i responses in cells expressing GPR120. Learn MoreStarting at: $119.00
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Acifran
Acifran is a hypolipidemic agent with higher potency than nicotinic acid and clofibrate. It reduces serum triglycerides and circulating LDL-cholesterol in vivo, without affecting liver weight or liver enzymes. Learn MoreStarting at: $99.00
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Leukotriene B4
Leukotriene B4 is a potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. It binds to BLT1 and BLT2 receptors and acts as a potent chemotactic agent and activator of leukocytes. Learn MoreStarting at: $269.00
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Pamoic acid disodium salt
Pamoic acid disodium salt is a GPR35 agonist that induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 and 65 nM respectively. Learn MoreStarting at: $60.00
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Ranitidine hydrochloride
Ranitidine hydrochloride is a potent, selective and competitive histamine H2 receptor antagonist that inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food in vivo. Learn MoreStarting at: $39.00
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Cinnabarinic acid
Cinnabarinic acid is a mGlu4 receptor agonist that activates mGlu4 receptors in transiently transfected HEK293 cells, decreases cAMP levels in native cultured cerebellar granule cells and also counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. Learn MoreStarting at: $129.00
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Xanthurenic acid
Xanthurenic acid attenuates cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors. Learn MoreStarting at: $39.00
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Histamine dihydrochloride
Histamine dihydrochloride is an an endogenous agonist at histamine receptors (H1-4) that stimulates gastric acid secretion and acts as a neurotransmitter in vivo. Learn MoreStarting at: $41.00
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L-Glutamic acid
L-Glutamic is the predominant excitatory transmitter in the mammalian central nervous system. It acts at ionotropic and metabotropic glutamate receptors. Learn MoreStarting at: $32.00
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Palmitoylethanolamide
Palmitoylethanolamide, a selective GPR55 agonist, is a substrate for fatty acid amide hydrolase (FAAH) and PEA-preferring acid amidase (PAA) and exhibits antinociceptive and anticonvulsant in vivo. Learn MoreStarting at: $65.00
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(+)-Fluprostenol
(+)-Fluprostenol, a prostaglandin F2α (FP) receptor agonist, stimulates intracellular calcium mobilization in cloned human ocular FP receptors, rat A7r5 cells and mouse 3T3 cells (EC50 values are 17.5, 19.1 and 37.3 nM respectively). Learn MoreStarting at: $55.00
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Doxepin hydrochloride
BMS 453 is a synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Learn MoreStarting at: $55.00
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H2L 5765834
Antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 values are 94, 463 and 752 nM respectively). Learn MoreStarting at: $139.00
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(S)-HexylHIBO
(S)-HexylHIBO is a group I mGlu receptor antagonist (Kb values are 30 and 61 μM at mGlu1a and mGlu5a receptors respectively). Learn MoreStarting at: $139.00
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HexylHIBO
HexylHIBO is a group I mGlu receptor antagonist (Ki values are 140 and 110 μM at mGlu1a and mGlu5a receptors respectively), which decreases sEPSCs in rat pyramidal neurons in vitro. Learn MoreStarting at: $129.00
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GRI 977143
GRI 977143 is a selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM), which inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Learn MoreStarting at: $135.00
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1-Oleoyl lysophosphatidic acid sodium salt
1-Oleoyl lysophosphatidic acid sodium salt is an endogenous agonist of the lysophospholipid receptors LPA1 and LPA2, which inhibits differentiation of neural stem cells (NSCs) into neurons. Learn MoreStarting at: $45.00
