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Search results for 'CT 47098'
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GGTI 297
GGTI 297 is a geranylgeranyltransferase I (GGTase-I) inhibitor (IC50 values are 135 and 418 nM for GGTase-I and FTase inhibition respectively), which inhibits RhoA prenylation leading to inactivation of RhoA/ROCK and a decrease in basal tone of the internal anal sphincter in vitro. Learn MoreStarting at: $149.00
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LY 379268 disodium salt
LY 379268 disodium salt is a sodium salt of LY 379268, a highly selective group II mGlu receptor agonist. Learn MoreStarting at: $295.00
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CHIR 99021 trihydrochloride
CHIR 99021 trihydrochloride is a hydrochloride salt of CHIR 99021, a highly selective GSK-3 inhibitor. Learn MoreStarting at: $189.00
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NU 9056
NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Learn MoreStarting at: $99.00
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PSB 1114
PSB 1114 is a potent, selective P2Y2 agonist (EC50 = 0.134 μM), which displays >60-fold selectivity versus P2Y4 and P2Y6 receptors. Learn MoreStarting at: $215.00
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(E)-FeCP-oxindole
(E)-FeCP-oxindole is a selective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 214 nM), which displays anticancer activity (IC50< 1 μM against B16 murine melanoma lines). Learn MoreStarting at: $179.00
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NPEC-caged-LY 379268
NPEC ((N)-1-(2-Nitrophenyl)ethoxycarbonyl) caged version of LY 379268, selective group II mGlu receptor agonist. Learn MoreStarting at: $345.00
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MRS 2211
MRS 2211 is a competitive P2Y13 receptor antagonist (pIC50 = 5.97) that displays > 20-fold selectivity over P2Y1 and P2Y12 receptors. Learn MoreStarting at: $89.00
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Ro 19-4603
Ro 19-4603 is a benzodiazepine inverse agonist, which binds with high affinity to both diazepam-sensitive (DS) and diazepam-insensitive (DI) GABAA receptors (Ki values are ~ 0.2 and ~ 2.6 nM for DS and DI receptors respectively). Learn MoreStarting at: $99.00
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SKF 83566 hydrobromide
SKF 83566 hydrobromide is a potent and selective D1-like dopamine receptor antagonist (Ki~ 0.56 nM for D1; KB = 2 μM for D2). Learn MoreStarting at: $79.00
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Anpirtoline hydrochloride
Anpirtoline hydrochloride is a highly potent 5-HT1B receptor agonist (Ki values are 28, 150 and 1490 nM at 5-HT1B, 5-HT1A and 5-HT2 receptors respectively), which decreases central serotonin synthesis and attenuates aggressive behavior in vivo. It also acts as an antagonist at 5-HT3 receptors (Ki = 29.5 nM) and is brain penetrant. Learn MoreStarting at: $119.00
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Fentanyl citrate
Fentanyl citrate is a potent and selective μ-opioid receptor agonist (Ki values are 7.0, 151 and 470 nM for μ-, δ- and κ-opioid receptors respectively), which displays antinociceptive activity in vivo. Learn MoreStarting at: $55.00
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Nitrocaramiphen hydrochloride
Nitrocaramiphen hydrochloride is a muscarinic antagonist with 71-fold selectivity for M1 over M2. Learn MoreStarting at: $95.00
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Carmoxirole hydrochloride
Carmoxirole hydrochloride is a selective, peripherally acting dopamine D2 receptor agonist. Learn MoreStarting at: $109.00
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Eltoprazine hydrochloride
Eltoprazine hydrochloride is a 5-HT1 and 5-HT2C receptor partial agonist (Ki values are 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively), which reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo. Learn MoreStarting at: $99.00
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Eticlopride hydrochloride
Eticlopride hydrochloride is a selective dopamine D2/D3 receptor antagonist (Ki values are 0.50 and 0.16 nM respectively). Learn MoreStarting at: $99.00
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Quinelorane hydrochloride
Quinelorane hydrochloride is a dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively. Learn MoreStarting at: $169.00
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AMN 082 dihydrochloride
AMN 082 dihydrochloride is the first selective mGlu7 agonist, which potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Learn MoreStarting at: $89.00
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XAC
XAC is an adenosine receptor antagonist (IC50 values are 1.8 and 114 nM at A1 and A2 receptors respectively). Learn MoreStarting at: $95.00
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Ocinaplon
Ocinaplon is a modulator of GABAA receptors, which displays modest selectivity for GABAA α1 receptors; and partial agonist activity at α2-, α3- and α5-containing receptors. Learn MoreStarting at: $139.00
