Search results for 'AP 24534'
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Fentanyl citrate
Fentanyl citrate is a potent and selective μ-opioid receptor agonist (Ki values are 7.0, 151 and 470 nM for μ-, δ- and κ-opioid receptors respectively), which displays antinociceptive activity in vivo. Learn MoreStarting at: $55.00
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Trap 101
Trap 101 is a potent and selective nociceptin/orphanin FQ (NOP) receptor antagonist. Learn MoreStarting at: $139.00
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Salvinorin A
Salvinorin A displays high affinity at both native (Ki = 4.3 nM) and cloned (Ki = 16 nM) κ-opioid receptors. Learn MoreStarting at: $139.00
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(±)-U-50488 hydrochloride
(±)-U-50488 hydrochloride is as elective κ-opioid agonist. Learn MoreStarting at: $99.00
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Buprenorphine hydrochloride
Buprenorphine hydrochloride, an ORL1 receptor agonist, displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors. Learn MoreStarting at: $40.00
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GNTI dihydrochloride
GNTI dihydrochloride is a highly potent κ opioid receptor antagonist (Ki = 0.18 nM for human cloned κ receptors expressed in CHO cells), which displays 208- and 799-fold selectivity over μ and δ receptors respectively. Learn MoreStarting at: $139.00
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SDM25N hydrochloride
SDM25N hydrochloride is a potent and highly selective non-peptide δ receptor antagonist (Ki values are 4.7, 3800 and 7900 nM for δ, κ and μ receptors respectively). Learn MoreStarting at: $125.00
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(±)-J 113397
(±)-J 113397 is a potent and selective NOP receptor antagonist (IC50 values are 2.3, 1400, 2200 and > 10000 nM for NOP, κ, μ and δ-opioid receptors respectively), which inhibits nociceptin/orphanin FQ-induced hyperalgesia in the mouse tail-flick test. Learn MoreStarting at: $189.00
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N-MPPP Hydrochloride
N-MPPP Hydrochloride is a high affinity κ agonist with no measured binding at μ or δ sites. Learn MoreStarting at: $110.00
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DIPPA hydrochloride
DIPPA hydrochloride is an irreversible and selective antagonist at the κ receptor, with persistent effect in vivo. Learn MoreStarting at: $100.00
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SB 205607 dihydrobromide
SB 205607 dihydrobromide is the first described non-peptide δ1 opioid receptor agonist with very high affinity and selectivity for the δ1 subtype (Ki values are 1.12, 2320 and 1790 nM at δ1, μ and κ receptors respectively). Learn MoreStarting at: $175.00
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Diprenorphine
Diprenorphine is a non-selective opioid receptor antagonist (Ki values are 0.017, 0.072 and 0.23 nM for κ-, μ- and δ-opioid receptors). Learn MoreStarting at: $125.00
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GR 89696 fumarate
Highly potent and selective κ-opioid agonist (IC50 = 0.04 nM) that may be selective for the putative κ2 receptor. Learn MoreStarting at: $135.00
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ICI 204,448 hydrochloride
ICI 204,448 hydrochloride is a peripherally acting κ agonist. Learn MoreStarting at: $95.00
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Cyprodime hydrochloride
Cyprodime hydrochloride is a selective μ-opioid receptor antagonist (Ki values are 5.4, 244.6 and 2187 nM for μ-, δ- and κ-opioid receptors respectively). Learn MoreStarting at: $130.00
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Clocinnamox mesylate
Clocinnamox mesylate is a systemically active, irreversible μ-opioid receptor antagonist (apparent Ki values are 0.7, 1.9 and 5.7 nM for mouse μ, δ and κ receptors respectively). Learn MoreStarting at: $95.00
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ICI 199,441 hydrochloride
ICI 199,441 hydrochloride is a highly potent κ agonist, 146-fold more active than U-50488 in vitro. Learn MoreStarting at: $95.00
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U-54494A hydrochloride
U-54494A hydrochloride is a κ-opioid agonist and anticonvulsant, which acts as an NMDA antagonist. Learn MoreStarting at: $105.00
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Naltriben mesylate
Naltriben mesylate is a selective and potent δ-opioid receptor antagonist (Ki values are 0.013, 19 and 152 nM for δ, μ and κ receptors respectively), which displays selectivity for the δ2 subtype in vivo. Learn MoreStarting at: $100.00
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Naltrindole hydrochloride
Naltrindole hydrochloride is a highly selective non-peptide δ opioid antagonist, showing 223- and 346-fold greater activity at δ than at μ and κ opioid receptors. Learn MoreStarting at: $95.00