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Search results for: 'LY 215840'

Search results for 'LY 215840'

(-)-5'-DMH-CBD

(-)-5'-DMH-CBD is an anandamide membrane transport inhibitor (IC50 = 14 μM) that is relatively metabolically stable, which displays some affinity for CB2 receptors but has only weak affinity for CB1 receptors and has no activity at VR1 receptors or FAAH. Learn More

Starting at: $149.00

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(±)-McN 5652

(±)-McN 5652 is a potent, high affinity serotonin re-uptake inhibitor; selective in viv, and displays moderate selectivity over noradrenalin and dopamine re-uptake in vitro (Ki values are 0.68, 2.9 and 36.8 nM for inhibition of serotonin, noradrenalin and dopamine uptake respectively in rat brain synaptosomes). Learn More

Starting at: $139.00

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LY 2365109 hydrochloride

LY 2365109 hydrochloride is a potent and selective glycine transporter 1 (GlyT1) inhibitor that induces a dose-dependent elevation in CSF levels of glycine, and enhances acetylcholine and dopamine release in the striatum and prefrontal cortex respectively. Learn More

Starting at: $149.00

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BTS 54-505 hydrochloride

BTS 54-505 hydrochloride is a potently active primary amine metabolite of sibutramine. Learn More

Starting at: $95.00

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YM 244769

YM 244769 is an inhibitor of the reverse mode of Na+/Ca2+ exchange (NCX) that inhibits Na+-dependent 45Ca2+ uptake with IC50 values of 18, 68 and 96 nM for CCL39 cells transfected with NCX3, NCX1 and NCX2 respectively. Learn More

Starting at: $125.00

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Concanamycin A

Concanamycin A is a specific inhibitor of V-type (vacuolar) H+-ATPase that blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines. Learn More

Starting at: $99.00

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Sertraline hydrochloride

Sertraline hydrochloride is a potent, orally active selective serotonin re-uptake inhibitor (SSRI). Learn More

Starting at: $109.00

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Org 24598 lithium salt

Org 24598 lithium salt is a selective inhibitor of the glial glycine transporter (GlyT1). pIC50 values are 6.9, <4 and <3 for GlyT1, GABA transporter and Glyt2 respectively. Learn More

Starting at: $139.00

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Bicifadine hydrochloride

Bicifadine hydrochloride is an orally active, potent antagonist of the noradrenalin transporter with antagonist activity at the 5-HT and dopamine transporters (IC50 values are 117 nM and 910 nM respectively). Learn More

Starting at: $139.00

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Paroxetine maleate

Paroxetine maleate is a highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter. Learn More

Starting at: $90.00

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OMDM-2

OMDM-2 is a metabolically stable inhibitor of anandamide cellular uptake that displays relatively low affinity for CB1 and CB2 receptors with Ki values of 5.1 and > 10 μM and for vanilloid VR1 receptors with EC50 value of 10 μM. Learn More

Starting at: $65.00

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Zimelidine dihydrochloride

Zimelidine dihydrochloride is a 5-HT re-uptake inhibitor that modulates nociception and induces hyperglycemia in vivo. Learn More

Starting at: $45.00

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(±)-Nipecotic acid

(±)-Nipecotic acid is a GABA uptake inhibitor with IC50 values of 8, 38, 106 and 2370 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively. Learn More

Starting at: $56.00

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Citalopram hydrobromide

Citalopram hydrobromide is a highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake with IC50 values of 1.8, 8800 and 41000 nM respectively. Learn More

Starting at: $105.00

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Desipramine hydrochloride

Desipramine hydrochloride is a tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters with Ki values of 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively. Learn More

Starting at: $41.00

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Cocaine hydrochloride

Cocaine hydrochloride, a competitive inhibitor of monoamine neurotransmitter transporters, inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with Ki values are 267, 392 and 872 nM respectively. Learn More

Starting at: $79.00

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MPDC

MM 77 dihydrochloride is a highly potent and fairly selective 5-HT1A ligand, which may be a full antagonist at postsynaptic receptors. Learn More

Starting at: $135.00

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(S)-SNAP 5114

BTS is a selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC50 ~ 5 mM), reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle. Learn More

Starting at: $135.00

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Guvacine hydrochloride

Guvacine hydrochloride is a specific GABA uptake inhibitor. IC50 values are 14, 58, 119 and 1870 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively. Learn More

Starting at: $125.00

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Org 25543 hydrochloride

Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2), which displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells. Learn More

Starting at: $139.00

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