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Search results for 'LY 215840'
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PF 04217903 mesylate
PF 04217903 mesylate is a highly selective, high affinity c-Met inhibitor that displays >1000-fold selectivity for c-Met over a panel of 208 kinases. Learn MoreStarting at: $189.00
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TC-I 15
TC-I 15 is a potent α2β1 integrin inhibitor. IC50 values for the inhibition of human platelet adhesion to type I collagen are 12 and 715 nM for platelets under static conditions and under flow, respectively. Learn MoreStarting at: $169.00
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5'-Fluoroindirubinoxime
5'-Fluoroindirubinoxime is an inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3) that displays antiproliferative activity against the MV4;11 cell line (expressing constitutively active FLT3) and a number of cancer cell lines, including SNU-638 (stomach carcinoma) and HT-1080 (fibrosarcoma). Learn MoreStarting at: $119.00
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RWJ 50271
CI 1020 is a highly selective, orally active, non-peptide endothelin-A receptor (ETA) antagonist (IC50 values are 0.3 and 480 nM for ETA and ETB receptors respectively). Learn MoreStarting at: $135.00
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Poly(I:C)
Poly(I:C) is a synthetic double-stranded RNA (dsRNA); Toll-like receptor 3 (TLR3) agonist. Learn MoreStarting at: $79.00
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Ro 08-2750
Ro 08-2750 is a non-peptide inhibitor of NGF that binds the NGF dimer (KD ~ 1 μM) possibly causing a conformational change, which inhibits binding selectively to p75NTR at submicromolar concentrations and to both p75NTR and TrkA at higher concentrations (> 5 μM). Learn MoreStarting at: $69.00
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A 286982
A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays respectively). Learn MoreStarting at: $139.00
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ANA 12
ANA 12 is a TrkB receptor antagonist, which demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively (IC50 values are 45.6 nM and 41.1 μM for the high and low affinity sites respectively). Learn MoreStarting at: $135.00
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BDNF (human)
BDNF (human) is a member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors which enhances the survival, growth and differentiation of neurons. Learn MoreStarting at: $239.00
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GR 144053 trihydrochloride
GR 144053 trihydrochloride is a potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). Learn MoreStarting at: $110.00
