Search results for 'gsk'

GSK 3787

GSK 3787 is a potent and selective peroxisome proliferator-activated receptor δ (PPARδ) antagonist (pIC50 = 6.6), which displays no measurable affinity for PPARα or PPARγ in vitro (pIC50< 5). Learn More

Starting at: $69.00

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SR 8278

SR 8278 is a Rev-Erbα antagonist; inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM) and blocks activity of Rev-Erbα agonist GSK 4112 in HEK293 cells. Learn More

Starting at: $115.00

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GSK 9027

GSK 9027 is a glucocorticoid receptor agonist (pIC50 = 8), which inhibits production of the proinflammatory mediator IL-6 in vivo. Learn More

Starting at: $135.00

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GSK 4112

GSK 4112 is a selective Rev-Erbα agonist (EC50 = 250 nM) which enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erbα; causes acute suppression of Bmal1 gene transcription. Learn More

Starting at: $100.00

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GSK 4716

GSK 4716 is a selective agonist at estrogen-related receptors ERRβ and ERR&gamma, which displays selectivity over ERRα and the classical estrogen receptors. Learn More

Starting at: $63.00

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