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Search results for 'the'
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Levcromakalim
Levcromakalim is an active enantiomer of the prototypical Kir6 (KATP) channel opener cromakalim. Learn MoreStarting at: $169.00
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MNI-caged-D-aspartate
MNI-caged-D-aspartate is a D-aspartate caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Learn MoreStarting at: $149.00
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RuBi-4AP
RuBi-4AP is a water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Learn MoreStarting at: $119.00
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DCPIB
DCPIB is a potent, selective blocker of the volume-sensitive anion channel (VSAC) that reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro. Learn MoreStarting at: $109.00
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KM 11060
KM 11060 increases the amount of functional CFTR at the plasma membrane (~75%). Learn MoreStarting at: $105.00
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N20C hydrochloride
N20C hydrochloride is a selective, non-competitive NMDA receptor antagonist that binds to the receptor-associated ion channel and prevents glutamate-induced Ca2+ influx. Learn MoreStarting at: $99.00
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(RS)-AMPA
(RS)-AMPA is a prototypical and defining agonist for the AMPA subgroup of ionotropic glutamate receptors. Learn MoreStarting at: $139.00
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Psora 4
Psora 4 is a potent KV1.3 channel blocker (EC50 = 3 nM) that preferentially binds the C-type inactivated state of the channel. Learn MoreStarting at: $145.00
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Veratridine
Veratridine is a Voltage-gated Na+ channel opener that increases intracellular Ca2+ with no effect on the Na+/Ca2+ exchanger. Learn MoreStarting at: $79.00
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Nonactin
Nonactin is a monovalent cation ionophore that displays selectivity for K+ and NH4+. It also inhibits P-glycoprotein-mediated efflux of chemotherapeutic agents in multiple-drug resistant cancer cells. Learn MoreStarting at: $99.00
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Dextromethorphan hydrobromide
Dextromethorphan hydrobromide is a Non-competitive, low affinity NMDA receptor antagonist with the effect of antitussive, anticonvulsive and neuroprotective. Learn MoreStarting at: $42.00
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AZ 10606120 dihydrochloride
AZ 10606120 dihydrochloride is a potent P2X7 receptor antagonist that binds in a positive cooperative manner to sites distinct from, but coupled to, the ATP binding site and acts as a negative allosteric modulator. Learn MoreStarting at: $121.00
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DCEBIO
DCEBIO stimulates Cl- secretion via the activation of hKCa3.1 (IK1) potassium channels and an apical Cl- conductance carried by the CFTR channel. Learn MoreStarting at: $99.00
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PNU 37883 hydrochloride
PNU 37883 hydrochloride acts as a novel antagonist selective for the vascular form of Kir6 (KATP) channel. It inhibits Kir6 currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Learn MoreStarting at: $125.00
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Salsolinol-1-carboxylic acid
Salsolinol-1-carboxylic acid is an amino acid that occurs naturally in the CNS. Learn MoreStarting at: $95.00
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L-Serine
L-Serine is an endogenous agonist at the inhibitory glycine receptor. Learn MoreStarting at: $33.00
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L-Alanine
L-Alanine is an Agonist at the inhibitory glycine receptor. Learn MoreStarting at: $33.00
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Hexamethonium bromide
Hexamethonium bromide is a Nicotinic receptor (nAChR) blocker at autonomic ganglia that induces changes in neuronal activity similar to the influences of glutamate in vitro. Learn MoreStarting at: $20.00
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T16Ainh-A01
T16Ainh-A01 is an inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial cells). Learn MoreStarting at: $119.00
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PHA 568487
PHA 568487 is an orally active and brain penetrant agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively). Learn MoreStarting at: $99.00
