Search results for 'inhibitor'
-
ML 298 hydrochloride
ML 298 hydrochloride is a selective inhibitor of phospholipase D2 (PLD2) (IC50 values are 355 and >20,000 nM for PLD2 and PLD1, respectively), which decreases invasive migration in U87-MG glioblastoma cells, without affecting cell viability. Learn MoreStarting at: $125.00
-
9-AC
9-AC is a Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI. Learn MoreStarting at: $65.00
-
L-Serine
L-Serine is an endogenous agonist at the inhibitory glycine receptor. Learn MoreStarting at: $33.00
-
L-Alanine
L-Alanine is an Agonist at the inhibitory glycine receptor. Learn MoreStarting at: $33.00
-
T16Ainh-A01
T16Ainh-A01 is an inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial cells). Learn MoreStarting at: $119.00
-
(-)-[3R,4S]-Chromanol 293B
680C91 is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) (Ki = 51 nM) which exhibits no activity against indoleamine 2,3-dioxygenase, monoamine oxidase A and B, 5-HT uptake or 5-HT1A, 1D, 2A and 2C receptors. Learn MoreStarting at: $140.00
-
ZK 200775
Benzamil is a Na+/Ca2+ exhanger (NCX) inhibitor (IC50 ~ 100 nM); TRPP3 channel blocker (IC50 = 1.1 μM for inhibition of Ca2+-activated TRPP3 channel activity). Learn MoreStarting at: $140.00
-
DMP 543
Indirubin-3'-oxime is aprotein kinase inhibitor and inhibits cyclin-dependent kinases (IC50 = 0.18 - 3.33 μM) and GSK-3β (IC50 = 0.19 μM). Learn MoreStarting at: $95.00
-
Vinpocetine
Vinpocetine is a phosphodiesterase inhibitor, selective for PDE1 (IC50 = 21 μM), which also blocks voltage-gated Na+ channels. Learn MoreStarting at: $109.00
-
CaCCinh-A01
Calcium-activated chloride channel (CaCC) inhibitor (IC50 ~ 10 μM), which inhibits CaCC currents in human bronchial and intestinal cells. Learn MoreStarting at: $99.00
-
NS 3623
NS 3623 is a human ether-a-go-go (hERG) KV11.1 potassium channel activator, which activates the IKr current and displays antiarrhythmic activity and exhibits potential dual mode of action at the hERG inhibitory site; may also act as a partial blocker of KV11.1 (hERG) channels. Learn MoreStarting at: $145.00
-
Hypotaurine
Endogenous inhibitory amino acid. Learn MoreStarting at: $75.00
-
Arcaine sulfate
Arcaine sulfate is a NO synthase inhibitor, acting as a competitive inhibitor at the polyamine site. Learn MoreStarting at: $80.00
-
ML 218 hydrochloride
ML 218 hydrochloride is a selective inhibitor of T-type calcium channels (IC50 values are 270 and 310 nM for Cav3.3 and Cav3.2 respectively in a patch EP assay). Learn MoreStarting at: $169.00
-
SKF 96365 hydrochloride
SKF 96365 hydrochloride is a store-operated Ca2+ entry (SOCE) inhibitor that inhibits STIM1.It also blocks TRPC channels, voltage-gated Ca2+ channels and potassium channels. Learn MoreStarting at: $115.00
-
Phenamil
Phenamil is TRPP3 channel inhibitor (IC50 = 0.14 μM), which also inhibits epithelial Na+ channels (Kd = 0.4 nM for a high affinity site on the epithelial Na+ channel). Learn MoreStarting at: $55.00
-
EIPA
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM), which inhibits the Na+/H+ exchanger (NHE). Learn MoreStarting at: $65.00
-
β-Alanine
β-Alanine is a non-specific endogenous agonist at the inhibitory glycine receptor. More selective than taurine, which slso distinguishes between GABA transporters (IC50 values are 19, 58, 110, 1320 and 5690 μM for rGAT-2, hGAT-3, rGAT-3, hBGT-3 and hGAT-1 respectively). Learn MoreStarting at: $49.00