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Search results for: 'contract number'

Search results for 'contract number'

6-Iodonordihydrocapsaicin

6-Iodonordihydrocapsaicin is a potent competitive vanilloid TRPV1 (VR1) receptor antagonist that inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro. Learn More

Starting at: $115.00

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KC 12291 hydrochloride

KC 12291 hydrochloride is an orally active atypical voltage-gated sodium channel blocker which inhibits sustained sodium currents (INaL) and prevents diastolic contracture in isolated atria in vitro (IC50 values are 9.6 and 0.55 - 0.79 μM respectively). Learn More

Starting at: $135.00

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Y-26763

Y-26763 is a kir6 (KATP) channel opener and active metabolite of Y-27152, which relaxes contracted rat aortic rings (IC50 = 0.027 mM) and inhibits glucose-induced insulin secretion in isolated human pancreatic β-cells in vitro. Learn More

Starting at: $130.00

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Penitrem A

Penitrem A is a potent and selective blocker of BKCa (KCa1.1) channels (IC50 values are 6.4 and 64.4 nM for BKCa channels containing α subunits only, and those containing α and β1 respectively), which blocks BKCa channels in both inside-out and cell-attached patches. Shown to enhance smooth muscle contraction in vitro and increase total peripheral resistance in vivo. Learn More

Starting at: $75.00

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Amlodipine besylate

Amlodipine besylate is a L-type calcium channel blocker that displays antihypertensive properties, which inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Learn More

Starting at: $50.00

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