Search results for 'CT 470'
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ML 298 hydrochloride
ML 298 hydrochloride is a selective inhibitor of phospholipase D2 (PLD2) (IC50 values are 355 and >20,000 nM for PLD2 and PLD1, respectively), which decreases invasive migration in U87-MG glioblastoma cells, without affecting cell viability. Learn MoreStarting at: $125.00
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L-651,582
L-651,582 is an orally active Ca2+ channel blocker which inhibits K+- and carbachol-stimulated Ca2+ influx (IC50 values are 500 and 935 nM respectively). Learn MoreStarting at: $149.00
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(R)-(+)-Bay K 8644
(R)-(+)-Bay K 8644 is a L-type Ca2+-channel blocker with negative inotropic and vasodilatatory effects in vivo. Learn MoreStarting at: $189.00
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(S)-(-)-Bay K 8644
(S)-(-)-Bay K 8644 is a L-type Ca2+-channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo. Learn MoreStarting at: $199.00
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NS 11021
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). Learn MoreStarting at: $139.00
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3-pyr-Cytisine
3-pyr-Cytisine is a high affinity α4β2 partial agonist that exhibits antidepressant-like effects in mouse models of antidepressant efficacy. Learn MoreStarting at: $139.00
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RN 1734
RN 1734 is a selective TRPV4 antagonist with IC50 values of 2.3, 5.9 and 3.2 μM for hTRPV4, mTRPV4 and rTRPV4 receptors respectively. Learn MoreStarting at: $95.00
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Levcromakalim
Levcromakalim is an active enantiomer of the prototypical Kir6 (KATP) channel opener cromakalim. Learn MoreStarting at: $169.00
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Cromakalim
Cromakalim is a prototypical Kir6 (KATP) channel opener that relaxes rabbit isolated portal vein with an IC50 value of 21 nM . Learn MoreStarting at: $139.00
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ACET
ACET is a potent and selective GluR5-containing kainate receptor antagonist that displays selectivity over GluR6-containing kainate, NMDA, AMPA and group I mGlu receptors. Learn MoreStarting at: $275.00
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AMTB hydrochloride
AMTB hydrochloride is a TRPM8 channel blocker that inhibits icilin- induced TRPM8 channel activation in a rat model. Learn MoreStarting at: $139.00
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Zatebradine hydrochloride
Zatebradine hydrochloride is a bradycardic agent that produces use-dependent inhibition of hyperpolarization-activated current If (HCN channel) in sinoatrial node cells and Purkinje fibres. Learn MoreStarting at: $109.00
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Benidipine hydrochloride
Benidipine hydrochloride is an orally active antihypertensive agent that inhibits L-, N- and T-type Ca2+ channels and also inhibits aldosterone-induced mineralocorticoid receptor activation. Learn MoreStarting at: $109.00
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RJR 2429 dihydrochloride
RJR 2429 dihydrochloride is a potent nAChR agonist that displays selectivity for α4β2 and α1βγδ. Learn MoreStarting at: $109.00
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Cl-HIBO
Cl-HIBO is a subtype-selective and strongly desensitising AMPA receptor agonist. Learn MoreStarting at: $179.00
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UBP 310
UBP 310 is a GLUK5 kainate receptor antagonist that also blocks recombinant homomeric GLUK7 receptors and displays 12,700-fold selectivity for GLUK5 over GLUK6. Learn MoreStarting at: $109.00
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Zacopride hydrochloride
Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist and 5-HT4 receptor agonist with Ki values of 0.38nM and 373nM respectively. Learn MoreStarting at: $105.00
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HC 067047
HC 067047 is a potent and selective TRPV4 antagonist that reversibly inhibits currents through mouse, human and rat TRPV4 orthologs. Learn MoreStarting at: $139.00
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SEN 12333
SEN 12333 is a α7 nicotinic acetylcholine receptor (nAChR) agonist that displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs with an IC50 value of 8.5 μM. Learn MoreStarting at: $125.00
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TC-P 262
TC-P 262 is a selective P2X3 and P2X2/3 receptor antagonist (pIC50 values are 7.39 and 6.68 respectively). Learn MoreStarting at: $109.00