You have no items in your shopping cart.
Search results for 'LY 215840'
-
CGK 733
CGK 733 is originally defined as a selective inhibitor of ATR and ATM kinases that decreases p21CIP1 levels in premature senescent MCF-7 and HCT-116 cells. Learn MoreStarting at: $105.00
-
AT 101
AT101, a natural product from cottonseed with a BH3-mimetic structure, was identified as a small molecule inhibitor of Bcl-2/Bcl-xL/Mcl-1 that potently induces apoptosis in various cancer cell lines. Learn MoreStarting at: $105.00
-
SJ 172550
SJ 172550 is a MDMX inhibitor, which reversibly binds MDMX (EC50 = 2.3 μM), and inhibits the MDMX-p53 interaction in cultured retinoblastoma cells; frees p53 to induce apoptosis. Learn MoreStarting at: $119.00
-
2,3-DCPE hydrochloride
2,3-DCPE hydrochloride selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Learn MoreStarting at: $75.00
-
AZ 10417808
AZ 10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC50 = 14.9 μM). Learn MoreStarting at: $139.00
-
CHM 1
CHM 1 is an inducer of apoptosis; displays potent antitumor ability in human hepatocellular carcinoma which inhibits tubulin polymerization in vitro and in vivo. Causes cell cycle arrest at G2/M phase by activation of Cdc2 kinase activity. Learn MoreStarting at: $100.00
-
Melphalan
Melphalan is a DNA alkylating agent; induces cytotoxicity through the formation of stable interstrand and intrastrand crosslinks within DNA which inhibits growth of PC-3 cells (IC50 values are 0.074 and 0.77 μM for sequential dosing and single dosing respectively). Learn MoreStarting at: $65.00
